SCHEMBL9686154

SCHEMBL9686154

CCOc1ccc(Oc2c[c]ccc2F)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.45
LTA4H P09960 2/20 0.44
L3MBTL1 Q9Y468 3/20 0.41
MAPT P10636 2/20 0.41
LMNA P02545 2/20 0.41
ATM Q13315 1/20 0.41
CACNA1C Q13936 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
GAA P10253 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
TSHR P16473 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
SYK P43405 1/20 0.35
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
PARP10 Q53GL7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL160145 0.83 L3MBTL1 (0.46) NQO1L3MBTL1MAPTLMNAGAA
SCHEMBL9685431 0.81 TEAD4 (0.38) MAPTLMNASLC6A2SLC6A4SLC6A3
SCHEMBL9685391 0.81 GAA (0.41) LTA4HL3MBTL1LMNASLC6A2SLC6A4
SCHEMBL8441722 0.81 ALDH1A1 (0.38) L3MBTL1MAPTLMNASLC6A2SLC6A4
SCHEMBL9560871 0.78 HTR2A (0.41) MAPTSLC6A2SLC6A4SLC6A3CYP1A2
SCHEMBL9560675 0.78 MAPT (0.38) MAPTSLC6A2SLC6A4SLC6A3PARP10
SCHEMBL919476 0.78 LTA4H (0.41) LTA4HL3MBTL1LMNASLC6A2SLC6A4
SCHEMBL9799346 0.77 FFAR4 (0.49) NQO1LTA4HMAPTLMNAGAA
SCHEMBL920057 0.75 LTA4H (0.63) NQO1LTA4HMAPTSLC6A2SLC6A4
SCHEMBL27270775 0.75 LTA4H (0.54) NQO1LTA4HMAPTSLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1044661-C Pesticides, insecticides, miticides and nematocides compositions containing new silanes derivatives HOECHST AG (DE) 1999-08-18 CN disclosed
CN-1032005-C Novel silane derivatives, formulations containing them and their use as pesticides HOECHST AG (DE) 1996-06-12 CN disclosed
CN-1027448-C Heterocyclic neophenan analogs and their use as anti-inflammatory agents HOECHST AG (DE) 1995-01-18 CN disclosed
CN-1091425-A Heterocyclic neophenan analogs, process for their preparation and their use as pesticides HOECHST AG (DE) 1994-08-31 CN disclosed
CN-1025501-C Process for preparing silane derivatives HOECHST AG (DE) 1994-07-20 CN disclosed
CN-1025502-C Process for preparing silane derivatives HOECHST AG (DE) 1994-07-20 CN disclosed
CN-1025470-C Pesticide, insecticide and acaricide compositions containing novel silane derivatives HOECHST AG (DE) 1994-07-20 CN disclosed
CN-1077588-A The agricultural chemicals, insecticide, the acaricidal nematicidal agent composition that contain novel silane derivs HOECHST AG (DE) 1993-10-27 CN disclosed
EP-0288810-B1 HETEROCYCLIC NEOPHANE ANALOGS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-02 EP disclosed
US-5116826-A SILAZANEOPHYL SULFIDES, AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-26 US disclosed
EP-0224024-B1 SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-20 EP disclosed
CN-1036570-A The new silylation sulfide of new alkyl sulfur compounds of azepine and azepine, they the preparation method, contain their preparation and they are as the application of sterilant HOECHST AG (DE) 1989-10-25 CN disclosed
EP-0336199-A1 Azaneophyl and silazaneophyl sulfides, process for their preparation, agents containing them, and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-11 EP disclosed
EP-0288810-A1 Heterocyclic neophane analogs, processes for their preparation and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-02 EP disclosed
CN-88102112-A Heterocyclic neophenan analogs, process for their preparation and their use as pesticides 1988-10-26 CN disclosed
US-4775664-A INSECTICIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1988-10-04 US disclosed
CN-87102981-A Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides 1988-03-02 CN disclosed
EP-0249015-A1 Silane derivatives, process for their preparation, agents containing them, and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-12-16 EP disclosed
CN-86107292-A Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides 1987-07-29 CN disclosed
EP-0224024-A1 Silane derivatives, process for their preparation, agents containing them and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-03 EP disclosed