Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124461 | 0.81 | LMNA (0.50) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL8124770 | 0.81 | LMNA (0.50) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL8124416 | 0.81 | LMNA (0.50) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL8129072 | 0.81 | LMNA (0.46) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL21986317 | 0.80 | LTA4H (0.41) | TDP1ALDH1A1SMN1; SMN2HTTCYP2A6 | |
| SCHEMBL8130021 | 0.80 | CYP19A1 (0.47) | LMNATDP1ALDH1A1CYP19A1GRM5 | |
| SCHEMBL8126130 | 0.79 | TDP1 (0.44) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL8121297 | 0.78 | LMNA (0.59) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL8126838 | 0.77 | LMNA (0.52) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL8126088 | 0.77 | LMNA (0.45) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990621-A | Insecticides, miticides and nematocides; 3-(3-fluoro-4-phenoxyphenyl, 3-(5-fluoro-3-phenoxypyrid-2-yl) or 3-(3-methyl-4-phenyl prop-1-ene | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |