Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799559 | 0.88 | CYP1A2 (0.44) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL10377449 | 0.86 | PDE4A (0.51) | ALDH1A1MAPTTSHRPDE4BPDE4D | |
| SCHEMBL10422375 | 0.84 | POLB (0.46) | KAT2BSMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL10378879 | 0.83 | SMN1; SMN2 (0.45) | KAT2BSMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL10377267 | 0.82 | KAT2B (0.42) | KAT2BSMN1; SMN2ALDH1A1MAPTGAA | |
| SCHEMBL10377279 | 0.82 | SMN1; SMN2 (0.44) | KAT2BSMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL10379176 | 0.80 | PKM (0.46) | KAT2BSMN1; SMN2ALDH1A1MAPTTHRB | |
| SCHEMBL8803476 | 0.78 | PDE4A (0.55) | ALDH1A1MAPTTSHRPDE4BPDE4D | |
| SCHEMBL7282270 | 0.77 | KAT2B (0.47) | KAT2BSMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL8804001 | 0.75 | GRIN2D (0.47) | KAT2BSMN1; SMN2POLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996212-A | Antiinflammatory and anti-hyperproliferative compounds | SCHERING CORPORATION (US) | 1991-02-26 | — | — | US | disclosed |
| US-4859669-A | Antiinflammatory and anti-hyperproliferative naphthyridin-4-ones | SCHERING CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |