SCHEMBL9799489

SCHEMBL9799489

CCOC(=O)CC(=O)c1cc[c]cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
ALDH1A1 P00352 2/20 0.51
KDM4E B2RXH2 1/20 0.51
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
TSHR P16473 1/20 0.44
MAPT P10636 2/20 0.43
HPGD P15428 1/20 0.43
NPC1 O15118 3/20 0.40
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL572 0.81 KMT2A (0.58) KMT2AMEN1ALDH1A1KDM4EMGAM
SCHEMBL124577 0.81 KMT2A (0.59) KMT2AMEN1ALDH1A1KDM4EMGAM
SCHEMBL31439645 0.80 KMT2A (0.57) KMT2AMEN1ALDH1A1KDM4EMGAM
SCHEMBL17433560 0.80 KMT2A (0.57) KMT2AMEN1ALDH1A1KDM4EMGAM
SCHEMBL28792148 0.80 KMT2A (0.57) KMT2AMEN1ALDH1A1KDM4EMGAM
SCHEMBL11515591 0.80 TSHR (0.66) KMT2AMEN1ALDH1A1KDM4EGAA
SCHEMBL17433641 0.80 KMT2A (0.57) KMT2AMEN1ALDH1A1KDM4EMGAM
SCHEMBL17433663 0.80 KMT2A (0.57) KMT2AMEN1ALDH1A1KDM4EMGAM
SCHEMBL8585196 0.80 ALDH1A1 (0.53) KMT2AMEN1ALDH1A1KDM4EMGAM
SCHEMBL17433632 0.80 KMT2A (0.57) KMT2AMEN1ALDH1A1KDM4EMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0224024-A1 Silane derivatives, process for their preparation, agents containing them and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-03 EP claimed
CN-1050878-A Novel silane derivs contains the preparation of this derivative and as the application of agricultural chemicals HOECHST AG (DE) 1991-04-24 CN disclosed
US-4990621-A Insecticides, miticides and nematocides; 3-(3-fluoro-4-phenoxyphenyl, 3-(5-fluoro-3-phenoxypyrid-2-yl) or 3-(3-methyl-4-phenyl prop-1-ene HOECHST AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed
US-4864027-A INSECTICIDES, NEMATOCIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-05 US disclosed
EP-0224024-A1 Silane derivatives, process for their preparation, agents containing them and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-03 EP disclosed