Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL572 | 0.87 | KMT2A (0.58) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL124577 | 0.87 | KMT2A (0.59) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL8085697 | 0.85 | CA12 (0.61) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL11515591 | 0.85 | TSHR (0.66) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL17433560 | 0.85 | KMT2A (0.57) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL28792148 | 0.85 | KMT2A (0.57) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL17433641 | 0.85 | KMT2A (0.57) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL17433663 | 0.85 | KMT2A (0.57) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL31439645 | 0.85 | KMT2A (0.57) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL6753757 | 0.85 | KMT2A (0.57) | ALDH1A1KMT2AMEN1KDM4EMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
| CN-108658991-B | Preparation method and application of 3, 5-disubstituted methylpyrazolo [1,5-a ] pyrimidine-7-phenolate analogue and derivative | 辽宁利锋科技开发有限公司 | 2023-12-15 | — | — | CN | disclosed |
| US-20210094954-A1 | PREPARATION METHODS AND APPLICATIONS OF 3,5-DISUBSTITUTED METHYLPYRAZOLO[1,5-A]PYRIMIDINE-7-HYDROXYLIC SALTS | XU LIFENG (US) | 2021-04-01 | — | — | US | disclosed |
| EP-0724560-B1 | THERMOSETTING COATING COMPOSITIONS | EASTMAN CHEM CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0724560-A1 | THERMOSETTING COATING COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1996-08-07 | — | — | EP | disclosed |
| US-5466863-A | 3-OXOADIPATE ESTERS OF POLYOLS WHICH ARE USEFUL AS CROSSLINKERS IN THERMOSETTING COATINGS | EASTMAN CHEMICAL COMPANY (US) | 1995-11-14 | — | — | US | disclosed |
| US-5412151-A | Oxoadipate esters of polyols | EASTMAN CHEMICAL COMPANY (US) | 1995-05-02 | — | — | US | disclosed |
| WO-1995011220-A1 | THERMOSETTING COATING COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1995-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | ALDH1A1 290/4885KMT2A 3400/4885MEN1 4353/4885 |
| US-20210094954-A1 | PREPARATION METHODS AND APPLICATIONS OF 3,5-DISUBSTITUTED METHYLPYRAZOLO[1,5-A]PYRIMIDINE-7-HYDROXYLIC SALTS | DHPS, NUDT1, DPYD | ALDH1A1 346/4885KMT2A 1925/4885MEN1 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.