Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.38 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.33 |
| ▸ | GLRB | P48167 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541137 | 0.85 | POLB (0.48) | POLBALDH1A1ALOX15SMN1; SMN2CYP1A2 | |
| SCHEMBL9835185 | 0.78 | POLB (0.44) | POLBALDH1A1ALOX15SMN1; SMN2CYP1A2 | |
| SCHEMBL28480301 | 0.76 | PDE4A (0.37) | ALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL2154134 | 0.74 | POLB (0.40) | POLBALDH1A1ALOX15SMN1; SMN2CYP1A2 | |
| SCHEMBL31589510 | 0.74 | POLB (0.41) | POLBALDH1A1ALOX15SMN1; SMN2CYP1A2 | |
| SCHEMBL7941748 | 0.72 | POLB (0.56) | POLBALDH1A1CYP1A2KDM4ECYP2C9 | |
| SCHEMBL1930777 | 0.72 | ALDH1A1 (0.56) | POLBALDH1A1ALOX15SMN1; SMN2CYP1A2 | |
| SCHEMBL139484 | 0.72 | POLB (0.56) | POLBALDH1A1ALOX15SMN1; SMN2CYP1A2 | |
| SCHEMBL396833 | 0.72 | CA2 (0.52) | POLBALDH1A1ALOX15SMN1; SMN2CYP1A2 | |
| SCHEMBL9812320 | 0.72 | CA2 (0.31) | POLBALDH1A1MAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228190-B1 | RIM POLYURETHANES COMPRISING MIXED DIAMINE CHAIN EXTENDERS AND PROCESS AND COMPOSITION FOR THEIR PRODUCTION | ETHYL CORPORATION (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0228190-A2 | RIM polyurethanes comprising mixed diamine chain extenders and process and composition for their production | ETHYL CORPORATION (US) | 1987-07-08 | — | — | EP | disclosed |
| US-4631298-A | REACTION INJECTION MOLDING POLYURETHANES | ETHYL CORPORATION (US) | 1986-12-23 | — | — | US | disclosed |