SCHEMBL9799598

SCHEMBL9799598

Cc1ccc(C(=NO)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
GAA P10253 5/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CA2 P00918 1/20 0.44
LMNA P02545 3/20 0.40
CES2 O00748 3/20 0.37
CES1 P23141 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.35
MLYCD O95822 1/20 0.34
PKM P14618 2/20 0.33
HTT P42858 2/20 0.33
ATM Q13315 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
HPGD P15428 1/20 0.33
NLRP1 Q9C000 1/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9799592 1.00 ALDH1A1 (0.46) ALDH1A1GAAALOX15HSD17B10CA2
SCHEMBL10150839 0.89 ALDH1A1 (0.43) ALDH1A1GAAALOX15HSD17B10CA2
SCHEMBL2677787 0.89 ALDH1A1 (0.43) ALDH1A1GAAALOX15HSD17B10CA2
SCHEMBL4668497 0.83 ALDH1A1 (0.63) ALDH1A1GAAALOX15HSD17B10CA2
SCHEMBL4668500 0.83 ALDH1A1 (0.63) ALDH1A1GAAALOX15HSD17B10CA2
SCHEMBL17122441 0.82 ALDH1A1 (0.47) ALDH1A1GAAALOX15HSD17B10CA2
SCHEMBL9799657 0.82 LMNA (0.53) ALDH1A1GAAALOX15HSD17B10CA2
SCHEMBL9799663 0.82 LMNA (0.53) ALDH1A1GAAALOX15HSD17B10CA2
SCHEMBL9799514 0.79 GAA (0.50) ALDH1A1GAAALOX15HSD17B10LMNA
SCHEMBL9799521 0.79 GAA (0.50) ALDH1A1GAAALOX15HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5041663-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1991-08-20 US disclosed
US-5032169-A Antidotes for herbicides CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
US-4759789-A Treating locus of plant before or during application of herbicide with oxime ether compound CIBA-GEIGY CORPORATION (US) 1988-07-26 US disclosed
US-4707182-A Phenoxine-ketal ethers, compositions containing them and the use thereof CIBA-GEIGY CORPORATION (US) 1987-11-17 US disclosed
US-4576628-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-03-18 US disclosed
US-4566901-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-01-28 US disclosed
EP-0094348-B1 OXIME ETHERS, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THE OXIME ETHERS AND THEIR USE CIBA-GEIGY AG (CH) 1985-07-24 EP disclosed
US-4530716-A Plant safening agent CIBA-GEIGY CORPORATION (US) 1985-07-23 US disclosed
EP-0094348-A1 Oxime ethers, process for their preparation, agents containing the oxime ethers and their use CIBA-GEIGY AG (CH) 1983-11-16 EP disclosed
EP-0089313-A1 Oxime ethers, process for their preparation, compositions containing the oxime ethers and their use CIBA-GEIGY AG (CH) 1983-09-21 EP disclosed