SCHEMBL9799657

SCHEMBL9799657

O/N=C(/c1ccc(Cl)cc1)C(F)(F)C(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.53
GAA P10253 3/20 0.53
ALOX15 P16050 2/20 0.43
ALDH1A1 P00352 1/20 0.43
HSD17B10 Q99714 1/20 0.43
NPSR1 Q6W5P4 2/20 0.41
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
TSHR P16473 3/20 0.37
CYP3A4 P08684 1/20 0.37
MAPK1 P28482 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
POLB P06746 3/20 0.34
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9799663 1.00 LMNA (0.53) LMNAGAAALOX15ALDH1A1HSD17B10
SCHEMBL9799935 0.88 LMNA (0.50) LMNAGAAALOX15ALDH1A1HSD17B10
SCHEMBL9799930 0.88 LMNA (0.50) LMNAGAAALOX15ALDH1A1HSD17B10
SCHEMBL10736396 0.85 GAA (0.58) LMNAGAAALOX15ALDH1A1HSD17B10
SCHEMBL9799912 0.85 GAA (0.58) LMNAGAAALOX15ALDH1A1HSD17B10
SCHEMBL9799906 0.85 GAA (0.58) LMNAGAAALOX15ALDH1A1HSD17B10
SCHEMBL10671556 0.83 LMNA (0.53) LMNAGAAALOX15ALDH1A1HSD17B10
SCHEMBL9799557 0.83 LMNA (0.53) LMNAGAAALOX15ALDH1A1HSD17B10
SCHEMBL9799598 0.82 ALDH1A1 (0.46) LMNAGAAALOX15ALDH1A1HSD17B10
SCHEMBL9799592 0.82 ALDH1A1 (0.46) LMNAGAAALOX15ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5041663-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1991-08-20 US disclosed
US-5032169-A Antidotes for herbicides CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
US-4759789-A Treating locus of plant before or during application of herbicide with oxime ether compound CIBA-GEIGY CORPORATION (US) 1988-07-26 US disclosed
US-4707182-A Phenoxine-ketal ethers, compositions containing them and the use thereof CIBA-GEIGY CORPORATION (US) 1987-11-17 US disclosed
US-4576628-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-03-18 US disclosed
US-4566901-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-01-28 US disclosed
EP-0094348-B1 OXIME ETHERS, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THE OXIME ETHERS AND THEIR USE CIBA-GEIGY AG (CH) 1985-07-24 EP disclosed
US-4530716-A Plant safening agent CIBA-GEIGY CORPORATION (US) 1985-07-23 US disclosed
EP-0094348-A1 Oxime ethers, process for their preparation, agents containing the oxime ethers and their use CIBA-GEIGY AG (CH) 1983-11-16 EP disclosed
EP-0089313-A1 Oxime ethers, process for their preparation, compositions containing the oxime ethers and their use CIBA-GEIGY AG (CH) 1983-09-21 EP disclosed