SCHEMBL9799643

SCHEMBL9799643

O=C(O)COc1ccccc1Oc1ccccn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.56
POLB P06746 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
GLA P06280 1/20 0.56
PTGDR2 Q9Y5Y4 4/20 0.49
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 2/20 0.49
HPGD P15428 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
SLC1A5 Q15758 1/20 0.47
ALOX15 P16050 1/20 0.46
TBXAS1 P24557 2/20 0.45
GRM4 Q14833 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
PKM P14618 1/20 0.43
RAB9A P51151 1/20 0.43
CASP1 P29466 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9732533 0.86 KDM4E (0.51) L3MBTL1POLBSMN1; SMN2GLAKDM4E
SCHEMBL9136230 0.84 LMNA (0.58) L3MBTL1POLBSMN1; SMN2GLAKDM4E
SCHEMBL176214 0.83 ALOX15 (0.55) L3MBTL1POLBSMN1; SMN2GLAPTGDR2
SCHEMBL30746861 0.83 ALOX15 (0.55) L3MBTL1POLBSMN1; SMN2GLAPTGDR2
Hydrochloric Acid SCHEMBL1280719 0.81 ALOX15 (0.53) L3MBTL1POLBSMN1; SMN2GLAPTGDR2
Hydrochloric Acid SCHEMBL31124708 0.81 ALOX15 (0.53) L3MBTL1POLBSMN1; SMN2GLAPTGDR2
SCHEMBL17946056 0.81 ALOX15 (0.59) SMN1; SMN2ALDH1A1ALOX15MEN1KMT2A
SCHEMBL11138427 0.80 KDM4E (0.66) L3MBTL1POLBSMN1; SMN2KDM4EALDH1A1
SCHEMBL340762 0.80 L3MBTL1 (0.80) L3MBTL1POLBSMN1; SMN2GLAPTGDR2
SCHEMBL29682135 0.80 L3MBTL1 (0.80) L3MBTL1POLBSMN1; SMN2GLAPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4488899-A Oxime derivatives for protecting plant crops CIBA-GEIGY CORPORATION (US) 1984-12-18 US claimed
US-4483707-A PLANT SAFTENING AGENTS CIBA-GEIGY CORPORATION (US) 1984-11-20 US claimed
US-5041663-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1991-08-20 US disclosed
US-5032169-A Antidotes for herbicides CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
US-4759789-A Treating locus of plant before or during application of herbicide with oxime ether compound CIBA-GEIGY CORPORATION (US) 1988-07-26 US disclosed
US-4707182-A Phenoxine-ketal ethers, compositions containing them and the use thereof CIBA-GEIGY CORPORATION (US) 1987-11-17 US disclosed
US-4698091-A 2-phenylpyrimidines, 2-naphthylpyrimidines and 2-heterocyclylpyrimidines as safeners for protecting cultivated plant against phytotoxic damage caused by herbicides CIBA-GEIGY CORPORATION (US) 1987-10-06 US disclosed
US-4674229-A SEEDS COATED WITH PLANT SAFENING AGENT CIBA-GEIGY CORPORATION (US) 1987-06-23 US disclosed
US-4576628-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-03-18 US disclosed
US-4566901-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-01-28 US disclosed
US-4530716-A Plant safening agent CIBA-GEIGY CORPORATION (US) 1985-07-23 US disclosed
US-4493726-A PLANT SAFENING AGENT CIBA GEIGY CORPORATION (US) 1985-01-15 US disclosed
US-4483707-A PLANT SAFTENING AGENTS CIBA-GEIGY CORPORATION (US) 1984-11-20 US disclosed
US-4348221-A FOR USE WITH CEREAL OR RICE CROPS CIBA-GEIGY CORPORATION (US) 1982-09-07 US disclosed