Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20774014 | 1.00 | MEN1 (0.36) | MEN1KMT2AMAPK1KDM4ECES2 | |
| SCHEMBL15062680 | 0.91 | — | — | |
| SCHEMBL15062522 | 0.91 | — | — | |
| SCHEMBL18832483 | 0.88 | ALDH1A1 (0.39) | MEN1KMT2AMAPK1APAF1NPC1 | |
| SCHEMBL1929100 | 0.88 | MEN1 (0.55) | MEN1KMT2AMAPK1KDM4ECES2 | |
| SCHEMBL15618683 | 0.83 | S100A4 (0.43) | S100A4 | |
| SCHEMBL693395 | 0.83 | MEN1 (0.55) | MEN1KMT2AMAPK1KDM4ECES2 | |
| SCHEMBL28981543 | 0.82 | ALDH1A1 (0.38) | MAPK1KDM4EPOLBMAPTSMN1; SMN2 | |
| SCHEMBL578457 | 0.81 | ALDH1A1 (0.58) | MEN1KMT2AMAPK1KDM4ECES2 | |
| SCHEMBL167625 | 0.79 | MEN1 (0.57) | MEN1KMT2AMAPK1KDM4ECES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312306-B2 | Substituted heterocyclic acyl-tripeptides useful as thrombin receptor modulators | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2007-12-25 | — | — | US | claimed |
| WO-2024037851-A1 | USE OF ADDITIVES FOR IMPROVING THE PROCESSING OF POLYETHYLENES | BASF SE (DE) | 2024-02-22 | — | — | WO | disclosed |
| WO-2024029204-A1 | COLORED CURABLE RESIN COMPOSITION, COLOR FILTER, DISPLAY DEVICE, AND SOLID-STATE IMAGE PICKUP ELEMENT | 住友化学株式会社 | 2024-02-08 | — | — | WO | disclosed |
| US-10844006-B2 | Trisamide compounds and compositions comprising the same | MILLIKEN & COMPANY (US) | 2020-11-24 | — | — | US | disclosed |
| EP-1592738-B1 | RESIN COMPOSITIONS | CIBA HOLDING INC (CH) | 2020-07-29 | — | — | EP | disclosed |
| US-10392395-B2 | Nitrogen-containing aromatic compounds and metal complexes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-08-27 | — | — | US | disclosed |
| EP-3426639-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | Milliken & Company (US) | 2019-01-16 | — | — | EP | disclosed |
| EP-2493890-B1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |
| US-20170260129-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & CO (US) | 2017-09-14 | — | — | US | disclosed |
| WO-2017156099-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & COMPANY (US) | 2017-09-14 | — | — | WO | disclosed |
| US-20080249269-A1 | Electret materials | CIBA CORP. | 2008-10-09 | — | — | US | disclosed |
| EP-1928936-A1 | PROCESS FOR IMPROVING THE FLOW PROPERTIES OF POLYMER MELTS | Ciba Holding Inc. (CH) | 2008-06-11 | — | — | EP | disclosed |
| US-7312306-B2 | Substituted heterocyclic acyl-tripeptides useful as thrombin receptor modulators | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-20070149663-A1 | Resin compositions | CIBA SPECIALTY CHEMICALS CORP. | 2007-06-28 | — | — | US | disclosed |
| WO-2007068766-A1 | MONO- AND MULTI-LAYER BLOWN FILMS | CIBA HOLDING INC. (CH) | 2007-06-21 | — | — | WO | disclosed |
| WO-2007039471-A1 | PROCESS FOR IMPROVING THE FLOW PROPERTIES OF POLYMER MELTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-04-12 | — | — | WO | disclosed |
| EP-1592738-A2 | RESIN COMPOSITIONS | Ciba SC Holding AG (CH) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004072168-A2 | RESIN COMPOSITIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-08-26 | — | — | WO | disclosed |
| EP-1140985-A1 | SUBSTITUTED HETEROCYCLIC ACYL-TRIPEPTIDES USEFUL AS THROMBIN RECEPTOR MODULATORS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035942-A1 | SUBSTITUTED HETEROCYCLIC ACYL-TRIPEPTIDES USEFUL AS THROMBIN RECEPTOR MODULATORS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2000-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844006-B2 | Trisamide compounds and compositions comprising the same | TELO2, TERT, H1-2 | MEN1 120/4885KMT2A 141/4885MAPK1 3847/4885 |
| US-10392395-B2 | Nitrogen-containing aromatic compounds and metal complexes | TYR, MT-CO2, SOD1 | MEN1 2740/4885KMT2A 1041/4885MAPK1 2683/4885 |
| US-20170260129-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | TELO2, TERT, H1-2 | MEN1 120/4885KMT2A 141/4885MAPK1 3847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.