Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | BACE1 | P56817 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730128 | 0.90 | MAPT (0.55) | MAPTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10733491 | 0.88 | MAPT (0.53) | MAPTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL13735822 | 0.74 | MAPT (0.57) | MAPTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9877381 | 0.74 | L3MBTL1 (0.57) | MAPTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8947258 | 0.72 | MAPT (0.55) | MAPTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9877332 | 0.71 | MAPT (0.54) | MAPTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL23909111 | 0.69 | MAPT (0.73) | MAPTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL13307806 | 0.69 | MEN1 (0.68) | MAPTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11678257 | 0.68 | MAPT (0.49) | MAPTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL17582594 | 0.67 | MAPT (0.49) | MAPTL3MBTL1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194164-B1 | N-CARBOXYALCOYL-2-OXO-3-DIARYL-5,6-TRIAZINES USEFUL AS THERAPEUTIC AGENTS | PIERRE FABRE MEDICAMENT (FR) | 1991-03-13 | — | — | EP | claimed |
| US-4677105-A | ANALGESICS | PF MEDICAMENT (FR) | 1987-06-30 | — | — | US | claimed |