Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PTGIR | P43119 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877194 | 0.80 | ALDH1A1 (0.44) | L3MBTL1MAPTTSHRKMT2AMEN1 | |
| SCHEMBL11620527 | 0.78 | CCNC (0.47) | L3MBTL1MAPTKMT2AMEN1PTGIR | |
| SCHEMBL9877233 | 0.76 | MEN1 (0.56) | MAPTTSHRJMJD6KMT2AMEN1 | |
| SCHEMBL9799766 | 0.74 | MAPT (0.68) | L3MBTL1MAPTTSHRKMT2AMEN1 | |
| SCHEMBL2927479 | 0.73 | MAPK1 (0.59) | L3MBTL1MAPTTSHRKMT2AMEN1 | |
| SCHEMBL9877332 | 0.73 | MAPT (0.54) | L3MBTL1MAPTTSHRKMT2AMEN1 | |
| SCHEMBL9876896 | 0.73 | MEN1 (0.47) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL11621957 | 0.71 | KMT2A (0.52) | L3MBTL1MAPTTSHRKMT2AMEN1 | |
| SCHEMBL27685211 | 0.70 | KMT2A (0.38) | L3MBTL1MAPTTSHRKMT2AMEN1 | |
| SCHEMBL11624535 | 0.69 | LMNA (0.47) | L3MBTL1MAPTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988725-A | Cardiovascular disorders, antiarrhythmia agents | STERLING DRUG INC. (US) | 1991-01-29 | — | — | US | disclosed |
| EP-0388654-A2 | Azole-1-alkanamides as antiarrhythmic agents and preparation thereof | STERLING DRUG INC. (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4916150-A | 1H-pyrazole-1-alkanamines antiarrhythmic compositions and use | STERLING DRUG INC. (US) | 1990-04-10 | — | — | US | disclosed |