Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800073 | 0.85 | RECQL (0.39) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL483182 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAALOX12NPC1RAB9A | |
| SCHEMBL9800114 | 0.84 | MTNR1A (0.37) | — | |
| SCHEMBL2837791 | 0.81 | ALDH1A1 (0.35) | SMN1; SMN2ALOX12KMT2AMEN1ALDH1A1 | |
| SCHEMBL2834383 | 0.80 | NPC1 (0.43) | SMN1; SMN2LMNANPC1RAB9AHTT | |
| SCHEMBL9800120 | 0.80 | RAB9A (0.43) | SMN1; SMN2LMNAALOX12NPC1RAB9A | |
| SCHEMBL9315506 | 0.79 | SMN1; SMN2 (0.36) | SMN1; SMN2LMNAALOX12NPC1RAB9A | |
| SCHEMBL9800100 | 0.79 | MTNR1A (0.41) | KMT2AMEN1MAPTTRPV1 | |
| SCHEMBL9800050 | 0.79 | MEN1 (0.34) | SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL2834346 | 0.78 | POLB (0.37) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068371-A | Photoinitiators for polymerization | CIBA-GEIGY CORPORATION (US) | 1991-11-26 | — | — | US | disclosed |