Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.52 |
| ▸ | MPO | P05164 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800364 | 1.00 | CSNK2A1 (0.52) | CSNK2A1MPOSLC6A4PTGS2PTGS1 | |
| SCHEMBL10494772 | 0.75 | CSNK2A1 (0.56) | CSNK2A1MPOSLC6A4HTR1AHTR1D | |
| Oxalic Acid SCHEMBL10693485 | 0.74 | KMT2A (0.58) | MPOSLC6A4HTR1AHTR1DHTR1B | |
| Oxalic Acid SCHEMBL10693498 | 0.74 | KMT2A (0.58) | MPOSLC6A4HTR1AHTR1DHTR1B | |
| SCHEMBL9800403 | 0.73 | CSNK2A1 (0.53) | CSNK2A1MPOSLC6A4HTR1AHTR1D | |
| SCHEMBL274224 | 0.72 | CSNK2A1 (0.67) | CSNK2A1MPOSLC6A4HTR1AHTR1D | |
| SCHEMBL8790446 | 0.72 | HTR1B (0.62) | HTR1AHTR1DHTR1B | |
| SCHEMBL8790450 | 0.72 | HTR1B (0.62) | HTR1AHTR1DHTR1B | |
| SCHEMBL8790440 | 0.72 | HTR1B (0.62) | HTR1AHTR1DHTR1B | |
| SCHEMBL8888939 | 0.69 | GABRP (0.47) | HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994483-A | 5-substituted-3-aminoalkyl indole derivatives for migraine | GLAXO GROUP LIMITED (GB) | 1991-02-19 | — | — | US | disclosed |