Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 8/20 | 0.43 |
| ▸ | HTR1B | P28222 | 6/20 | 0.43 |
| ▸ | HTR1D | P28221 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494772 | 0.87 | CSNK2A1 (0.56) | CSNK2A1HTR1AHTR1BHTR1DHTR2A | |
| SCHEMBL9800390 | 0.84 | CSNK2A1 (0.50) | CSNK2A1HTR1AHTR1BHTR1DHTR2A | |
| SCHEMBL9800423 | 0.84 | HTR1B (0.54) | CSNK2A1HTR1AHTR1BHTR1DHTR2A | |
| SCHEMBL9800331 | 0.79 | HTR1A (0.66) | HTR1AHTR1BHTR1DHTR2AHTR2B | |
| SCHEMBL14964100 | 0.76 | CSNK2A1 (0.63) | CSNK2A1HTR1AHTR1BHTR1DHTR2A | |
| SCHEMBL9765114 | 0.76 | HTR1D (0.65) | CSNK2A1HTR1AHTR1BHTR1DHTR2A | |
| SCHEMBL10755540 | 0.76 | CSNK2A1 (0.52) | CSNK2A1HTR1AHTR1BHTR1DHTR2A | |
| SCHEMBL8785278 | 0.74 | HTR1A (0.67) | CSNK2A1HTR1AHTR1BHTR1DHTR2A | |
| Oxalic Acid SCHEMBL9800367 | 0.74 | KMT2A (0.60) | HTR1AHTR1BHTR1DHTR2AHTR2B | |
| SCHEMBL9800356 | 0.73 | CSNK2A1 (0.52) | CSNK2A1HTR1AHTR1BHTR1DMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994483-A | 5-substituted-3-aminoalkyl indole derivatives for migraine | GLAXO GROUP LIMITED (GB) | 1991-02-19 | — | — | US | disclosed |