Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 10/20 | 0.53 |
| ▸ | HTR1B | P28222 | 10/20 | 0.53 |
| ▸ | HTR1A | P08908 | 10/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | HTR5A | P47898 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR1E | P28566 | 1/20 | 0.53 |
| ▸ | HTR1F | P30939 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800358 | 0.90 | HTR1D (0.56) | HTR1DHTR1BHTR1AHTR2AHTR7 | |
| SCHEMBL9800416 | 0.85 | HTR1B (0.54) | HTR1DHTR1BHTR1AHTR2AHTR7 | |
| SCHEMBL9800378 | 0.81 | HTR1A (0.48) | HTR1DHTR1BHTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL9800406 | 0.81 | HTR1A (0.64) | HTR1DHTR1BHTR1AHTR2AHTR7 | |
| SCHEMBL9800349 | 0.80 | HTR1A (0.80) | HTR1DHTR1BHTR1AHTR2AHTR7 | |
| Oxalic Acid SCHEMBL9800389 | 0.80 | HTR1A (0.72) | HTR1DHTR1BHTR1AHTR2AHTR7 | |
| SCHEMBL9800384 | 0.80 | HTR1D (0.59) | HTR1DHTR1BHTR1AHTR2AHTR7 | |
| SCHEMBL9765120 | 0.79 | HTR1D (0.68) | HTR1DHTR1BHTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL9800365 | 0.79 | HTR1A (0.79) | HTR1DHTR1BHTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL9800422 | 0.78 | HTR1A (0.77) | HTR1DHTR1BHTR1AHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994483-A | 5-substituted-3-aminoalkyl indole derivatives for migraine | GLAXO GROUP LIMITED (GB) | 1991-02-19 | — | — | US | disclosed |