Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | HTR1B | P28222 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR1E | P28566 | 1/20 | 0.48 |
| ▸ | HTR1F | P30939 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR5A | P47898 | 1/20 | 0.48 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | SPR | P35270 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800430 | 0.86 | MTNR1A (0.60) | HTR1AHTR1DHTR1BALDH1A1HTR2A | |
| SCHEMBL9800416 | 0.85 | HTR1B (0.54) | HTR1AHTR1DHTR1BALDH1A1HTR2A | |
| SCHEMBL9800344 | 0.82 | MTNR1A (0.62) | HTR1AHTR1DHTR1BALDH1A1HTR2A | |
| Hydrochloric Acid SCHEMBL9800419 | 0.82 | MPO (0.57) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL9800358 | 0.82 | HTR1D (0.56) | HTR1AHTR1DHTR1BALDH1A1HTR2A | |
| SCHEMBL9800380 | 0.81 | HTR1D (0.53) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL9800384 | 0.80 | HTR1D (0.59) | HTR1AHTR1DHTR1BALDH1A1HTR2A | |
| SCHEMBL9800332 | 0.80 | HTR1A (0.59) | HTR1AHTR1DHTR1BALDH1A1HTR2A | |
| SCHEMBL9800346 | 0.79 | MPO (0.57) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9800399 | 0.78 | HTR1A (0.57) | HTR1AHTR1DHTR1BALDH1A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994483-A | 5-substituted-3-aminoalkyl indole derivatives for migraine | GLAXO GROUP LIMITED (GB) | 1991-02-19 | — | — | US | disclosed |