Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.73 |
| ▸ | ATM | Q13315 | 1/20 | 0.73 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | FOS | P01100 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | JUN | P05412 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800427 | 1.00 | GAA (0.73) | GAAATMSIGMAR1FOSTTR | |
| SCHEMBL6095764 | 0.87 | KMT2A (0.63) | GAAATMSIGMAR1ALOX15KDM4E | |
| SCHEMBL6095767 | 0.87 | KMT2A (0.63) | GAAATMSIGMAR1ALOX15KDM4E | |
| SCHEMBL4211354 | 0.84 | GAA (0.59) | GAAATMFOSTTRJUN | |
| SCHEMBL14731883 | 0.84 | GAA (1.00) | GAAATMSIGMAR1POLBMAPK1 | |
| SCHEMBL7929020 | 0.82 | SIGMAR1 (0.63) | GAAATMSIGMAR1ALOX15KDM4E | |
| SCHEMBL7929023 | 0.82 | SIGMAR1 (0.63) | GAAATMSIGMAR1ALOX15KDM4E | |
| Mesodihydroguaiaretic Acid SCHEMBL4852003 | 0.81 | FOS (0.84) | GAAATMFOSTTRJUN | |
| SCHEMBL11861031 | 0.81 | FOS (0.63) | GAAATMFOSTTRJUN | |
| SCHEMBL4201306 | 0.81 | GAA (0.61) | GAAATMFOSTTRJUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039801-A | Refluxing in alcoholic solution | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 1991-08-13 | — | — | US | disclosed |