Sugi Predict

Sugi Predict / Compounds / SCHEMBL4201306

SCHEMBL4201306

SCHEMBL4201306

COc1cc(CNC(c2ccccc2)c2ccccc2)ccc1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 3/20 0.61
▸ ATM Q13315 2/20 0.61
▸ KMT2A Q03164 2/20 0.58
▸ MEN1 O00255 1/20 0.58
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ ALDH1A1 P00352 2/20 0.53
▸ KDM4E B2RXH2 1/20 0.53
▸ POLB P06746 1/20 0.53
▸ MAPT P10636 1/20 0.53
▸ HPGD P15428 1/20 0.53
▸ ALOX15 P16050 1/20 0.53
▸ HSD17B10 Q99714 1/20 0.53
▸ TDP1 Q9NUW8 2/20 0.52
▸ TRPV1 Q8NER1 1/20 0.52
▸ FOS P01100 1/20 0.51
▸ TTR P02766 1/20 0.51
▸ JUN P05412 1/20 0.51
▸ NR3C1 P04150 1/20 0.51
▸ HSD17B1 P14061 1/20 0.51
▸ HSD17B2 P37059 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4201371 0.87 TDP1 (0.54) GAAATMKMT2AALDH1A1KDM4E
SCHEMBL4210480 0.86 KMT2A (0.60) GAAATMKMT2AMEN1L3MBTL1
SCHEMBL4211354 0.84 GAA (0.59) GAAATMKMT2AALDH1A1KDM4E
SCHEMBL23216976 0.82 KMT2A (0.57) GAAATMKMT2AMEN1ALDH1A1
SCHEMBL9800427 0.81 GAA (0.73) GAAATMKMT2AALDH1A1KDM4E
SCHEMBL9800428 0.81 GAA (0.73) GAAATMKMT2AALDH1A1KDM4E
SCHEMBL11861031 0.80 FOS (0.63) GAAATMKMT2AMEN1ALDH1A1
SCHEMBL11069853 0.79 GAA (0.67) GAAATMKMT2AALDH1A1KDM4E
SCHEMBL16057469 0.78 GAA (0.64) GAAATMKMT2AALDH1A1KDM4E
SCHEMBL29224597 0.78 ERCC1 (0.74) GAAKMT2AMEN1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 — — US claimed
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same SYMRISE AG (DE) 2025-02-27 — — US claimed
WO-2025026525-A1 HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS SYMRISE AG (DE) 2025-02-06 — — WO claimed
EP-4469439-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-12-04 — — EP claimed
CN-118984825-A Novel cooling agent and preparation containing same 西姆莱斯股份公司 2024-11-19 — — CN claimed
EP-4452941-A1 ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-10-30 — — EP claimed
US-20240058259-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS FIRMENICH SA (CH) 2024-02-22 — — US claimed
US-20240000746-A1 New Cooling Agents and Preparations Containing Them SYMRISE AG (DE) 2024-01-04 — — US claimed
EP-4247791-A2 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2023-09-27 — — EP claimed
WO-2023144326-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-08-03 — — WO claimed
US-20210100245-A1 SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS BEDOUKIAN RESEARCH, INC. (US) 2021-04-08 — — US claimed
US-20200188289-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS FIRMENICH SA (CH) 2020-06-18 — — US claimed
EP-3624757-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS Firmenich SA (CH) 2020-03-25 — — EP claimed
CN-110621287-A Composition comprising essential oils 弗门尼舍有限公司 2019-12-27 — — CN claimed
US-10392371-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2019-08-27 — — US claimed
WO-2018211420-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS FIRMENICH SA (CH) 2018-11-22 — — WO claimed
CN-101400636-A Para-substituted 2-alkoxyphenol compounds GIVAUDAN SA (CH) 2009-04-01 — — CN claimed
US-20090035364-A1 PARA-SUBSTITUTED 2-ALKOXYPHENOL COMPOUNDS GIVAUDAN SA (CH) 2009-02-05 — — US claimed
EP-1996535-A2 PARA-SUBSTITUTED 2-ALKOXYPHENOL COMPOUNDS Givaudan SA (CH) 2008-12-03 — — EP claimed
WO-2007104175-A2 PARA-SUBSTITUTED 2-ALKOXYPHENOL COMPOUNDS GIVAUDAN SA (CH) 2007-09-20 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210100245-A1 SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS NOTUM, SGMS1, COASY GAA 3697/4885ATM 4497/4885KMT2A 2193/4885
US-10392371-B2 Compounds useful as modulators of TRPM8 TRPM8, TRPM4, TRPM6 GAA 3828/4885ATM 1817/4885KMT2A 3630/4885
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same TAS2R5, TAS2R7, TAS2R8 GAA 88/4885ATM 4230/4885KMT2A 2748/4885
US-20240000746-A1 New Cooling Agents and Preparations Containing Them TTPA, TREH, TAS2R45 GAA 2325/4885ATM 3164/4885KMT2A 4030/4885
US-20250163006-A1 New Coolants, and Preparations Containing Same TTR, TAS2R5, TAS2R50 GAA 925/4885ATM 2716/4885KMT2A 3992/4885
US-20090035364-A1 PARA-SUBSTITUTED 2-ALKOXYPHENOL COMPOUNDS EBP, CYP1A1, CYP2E1 GAA 4473/4885ATM 1457/4885KMT2A 523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.