Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839886 | 1.00 | NOS3 (0.37) | NOS3NOS1NOS2ALDH1A1CA2 | |
| SCHEMBL9516593 | 0.88 | NOS3 (0.38) | NOS3NOS1NOS2ALDH1A1MEN1 | |
| SCHEMBL2634911 | 0.85 | ALDH1A1 (0.41) | ALDH1A1DDAH1TSHRENPEPCHRM1 | |
| SCHEMBL28172828 | 0.82 | MME (0.38) | NOS3NOS1NOS2ALDH1A1CA2 | |
| SCHEMBL28544923 | 0.81 | MEN1 (0.39) | ALDH1A1CA2DDAH1MEN1KMT2A | |
| SCHEMBL9640726 | 0.81 | RNPEP (0.44) | NOS3NOS1NOS2ALDH1A1CA2 | |
| SCHEMBL30508517 | 0.81 | NOS3 (0.57) | NOS3NOS1NOS2DDAH1KMT2A | |
| SCHEMBL839217 | 0.81 | LCK (0.42) | NOS3NOS1NOS2ALDH1A1CA2 | |
| Bicarbonate SCHEMBL27364872 | 0.80 | ALDH1A1 (0.44) | ALDH1A1CA2MEN1KMT2ATSHR | |
| Bicarbonate SCHEMBL9083427 | 0.80 | ALDH1A1 (0.44) | ALDH1A1CA2MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1335875-A | Solvent-based pen inks | BERROL COMPANY (US) | 2002-02-13 | — | — | CN | disclosed |
| EP-0415939-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-03-13 | — | — | EP | disclosed |
| WO-1989009218-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-10-05 | — | — | WO | disclosed |