Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800586 | 0.88 | NOS3 (0.37) | NOS3NOS1NOS2HSD17B10ENPEP | |
| SCHEMBL839886 | 0.88 | NOS3 (0.37) | NOS3NOS1NOS2HSD17B10ENPEP | |
| SCHEMBL28988515 | 0.84 | NOS3 (0.35) | NOS3NOS1NOS2HSD17B10BLM | |
| SCHEMBL29050838 | 0.82 | CHRM1 (0.37) | NOS3NOS1NOS2HSD17B10CHRM1 | |
| SCHEMBL3328503 | 0.81 | ALDH1A1 (0.44) | NOS3NOS1NOS2ENPEPALDH1A1 | |
| SCHEMBL9396104 | 0.81 | NOS3 (0.43) | NOS3NOS1NOS2ALDH1A1KMT2A | |
| SCHEMBL6133300 | 0.76 | ALDH1A1 (0.50) | NOS3NOS1NOS2HSD17B10ALDH1A1 | |
| SCHEMBL16443443 | 0.76 | FOLH1 (0.52) | NOS3NOS1NOS2HSD17B10ENPEP | |
| SCHEMBL2634911 | 0.74 | ALDH1A1 (0.41) | ENPEPALDH1A1TSHRCHRM1AKR1A1 | |
| SCHEMBL30442680 | 0.74 | TET2 (0.52) | NOS3NOS1NOS2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341409-B1 | Platinum (II) complexes, their preparation and use as antitumour agents | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-12-29 | — | — | EP | disclosed |
| EP-0415939-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-03-13 | — | — | EP | disclosed |
| EP-0341409-A1 | Platinum (II) complexes, their preparation and use as antitumour agents | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1989-11-15 | — | — | EP | disclosed |
| WO-1989009218-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-10-05 | — | — | WO | disclosed |