Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.50 |
| ▸ | CCR8 | P51685 | 5/20 | 0.50 |
| ▸ | CCR5 | P51681 | 3/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.45 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586563 | 0.86 | CCR1 (0.50) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL24368249 | 0.84 | CCR1 (0.51) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL21525701 | 0.80 | CCR1 (0.47) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL4330878 | 0.78 | CCR1 (0.45) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL3594386 | 0.78 | SLC22A12 (0.46) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL7450182 | 0.77 | CCR1 (0.55) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL874272 | 0.76 | PSMD14 (0.67) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL24338582 | 0.75 | ALDH1A1 (0.49) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL12093369 | 0.74 | CCR1 (0.56) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL5544307 | 0.73 | CCR1 (0.55) | CCR1CCR8CCR5PSMD14COPS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261539-B1 | SUBSTITUTED PHENYL-SULPHON AMIDES | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |