Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800648 | 1.00 | MT-CO2 (0.32) | MT-CO2DDB1CRBNNFKB1NFKB2 | |
| SCHEMBL2350718 | 0.88 | KMT2A (0.34) | NFKB1NFKB2RELAKMT2A | |
| SCHEMBL2350728 | 0.88 | KMT2A (0.34) | NFKB1NFKB2RELAKMT2A | |
| SCHEMBL8908787 | 0.87 | THRB (0.38) | MT-CO2DDB1CRBNNFKB1NFKB2 | |
| SCHEMBL8908784 | 0.87 | THRB (0.38) | MT-CO2DDB1CRBNNFKB1NFKB2 | |
| SCHEMBL3672475 | 0.86 | BTK (0.36) | KMT2A | |
| SCHEMBL5131640 | 0.84 | BTK (0.36) | KMT2A | |
| SCHEMBL4996407 | 0.84 | BTK (0.36) | KMT2A | |
| SCHEMBL2712968 | 0.83 | TSHR (0.37) | KMT2A | |
| SCHEMBL9744375 | 0.83 | TSHR (0.37) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416373-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | disclosed |