Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.88 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | IDH1 | O75874 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E1501 SCHEMBL14031569 | 0.94 | ALDH1A1 (1.00) | ALDH1A1TDP1L3MBTL1MAPK1SLC6A2 | |
| E1501 SCHEMBL901210 | 0.94 | ALDH1A1 (1.00) | ALDH1A1TDP1L3MBTL1MAPK1SLC6A2 | |
| E1501 SCHEMBL43745 | 0.94 | ALDH1A1 (1.00) | ALDH1A1TDP1L3MBTL1MAPK1SLC6A2 | |
| E1501 SCHEMBL28201296 | 0.94 | ALDH1A1 (1.00) | ALDH1A1TDP1L3MBTL1MAPK1SLC6A2 | |
| E1501 SCHEMBL4650267 | 0.92 | ALDH1A1 (0.88) | ALDH1A1TDP1L3MBTL1MAPK1SLC6A2 | |
| E1501 SCHEMBL1256238 | 0.92 | ALDH1A1 (0.96) | ALDH1A1TDP1L3MBTL1MAPK1SLC6A2 | |
| E1501 SCHEMBL18954294 | 0.92 | ALDH1A1 (0.96) | ALDH1A1TDP1L3MBTL1MAPK1SLC6A2 | |
| E1501 SCHEMBL28928069 | 0.92 | ALDH1A1 (0.96) | ALDH1A1TDP1L3MBTL1MAPK1SLC6A2 | |
| E1501 SCHEMBL183528 | 0.92 | ALDH1A1 (0.96) | ALDH1A1TDP1L3MBTL1MAPK1SLC6A2 | |
| E1501 SCHEMBL30579458 | 0.92 | ALDH1A1 (0.96) | ALDH1A1TDP1L3MBTL1MAPK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073640-A | CYCLICDIHYDROXY COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-12-17 | — | — | US | disclosed |