Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 10/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800808 | 0.93 | TSHR (0.45) | KDM1APTGDR2PPARDPPARAACACB | |
| SCHEMBL9800824 | 0.84 | FFAR4 (0.51) | KDM1AMEN1KMT2AABL1 | |
| SCHEMBL10415568 | 0.84 | RARB (0.41) | HSD17B10 | |
| SCHEMBL9800825 | 0.83 | FFAR4 (0.43) | KMT2A | |
| SCHEMBL9800817 | 0.82 | RARB (0.45) | PPARAMEN1KMT2A | |
| SCHEMBL9800787 | 0.78 | RARB (0.40) | PTGDR2HSD17B10 | |
| SCHEMBL9800791 | 0.77 | FFAR4 (0.49) | ABL1 | |
| SCHEMBL9800804 | 0.77 | CTRC (0.44) | PTGDR2MEN1KMT2AABL1 | |
| SCHEMBL9800840 | 0.77 | NPC1 (0.36) | KDM1AACACBMEN1KMT2A | |
| SCHEMBL11409056 | 0.76 | NPC1 (0.39) | KDM1AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249081-B1 | TRANSHEXAHYDROTEREPHTALIC ACID ESTER DERIVATIVES | Sato, Hisato (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4946991-A | Liquid ccrystals or their additives | SATO HISATO (JP) | 1990-08-07 | — | — | US | disclosed |