Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 9/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800831 | 0.93 | KDM1A (0.47) | TSHRHSD17B10PTGDR2KDM1APPARD | |
| SCHEMBL10415568 | 0.86 | RARB (0.41) | HSD17B10RARBTHRATHRBAKR1C2 | |
| SCHEMBL9800787 | 0.85 | RARB (0.40) | HSD17B10PTGDR2RARBTHRATHRB | |
| SCHEMBL9800804 | 0.84 | CTRC (0.44) | PTGDR2RARBAKR1C2AKR1C1 | |
| SCHEMBL9800791 | 0.84 | FFAR4 (0.49) | RARB | |
| SCHEMBL9800817 | 0.82 | RARB (0.45) | PPARARARBTHRATHRB | |
| SCHEMBL9800839 | 0.78 | RARB (0.36) | TSHRHSD17B10RARBTHRATHRB | |
| SCHEMBL9800824 | 0.77 | FFAR4 (0.51) | KDM1A | |
| SCHEMBL11415316 | 0.77 | SPHK1 (0.41) | — | |
| SCHEMBL9800825 | 0.76 | FFAR4 (0.43) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249081-B1 | TRANSHEXAHYDROTEREPHTALIC ACID ESTER DERIVATIVES | Sato, Hisato (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4946991-A | Liquid ccrystals or their additives | SATO HISATO (JP) | 1990-08-07 | — | — | US | disclosed |