Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.44 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10415568 | 0.95 | RARB (0.41) | RARBS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL9800787 | 0.85 | RARB (0.40) | RARBS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL9800804 | 0.84 | CTRC (0.44) | RARBS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL9800791 | 0.84 | FFAR4 (0.49) | RARBRARARARG | |
| SCHEMBL9800824 | 0.84 | FFAR4 (0.51) | MEN1ALDH1A1KMT2A | |
| SCHEMBL9800825 | 0.83 | FFAR4 (0.43) | ALDH1A1KMT2ATHRB | |
| SCHEMBL9800808 | 0.82 | TSHR (0.45) | RARBTHRATHRBPPARA | |
| SCHEMBL13198355 | 0.82 | AKR1C2 (0.47) | RARBS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL9800831 | 0.82 | KDM1A (0.47) | MEN1KMT2APPARA | |
| SCHEMBL4544897 | 0.80 | THRB (0.60) | RARBS1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249081-B1 | TRANSHEXAHYDROTEREPHTALIC ACID ESTER DERIVATIVES | Sato, Hisato (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4946991-A | Liquid ccrystals or their additives | SATO HISATO (JP) | 1990-08-07 | — | — | US | disclosed |