Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 9/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | CYCS | P99999 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800954 | 0.87 | PDE5A (0.39) | TOP1CYCSPTPN1STAT3STAT1 | |
| SCHEMBL9800961 | 0.82 | STAT3 (0.40) | TOP1CYCSPTPN1STAT3STAT1 | |
| SCHEMBL29257448 | 0.80 | TOP1 (0.55) | TOP1CYCS | |
| SCHEMBL30382242 | 0.79 | TOP1 (0.54) | TOP1CYCS | |
| SCHEMBL12459750 | 0.79 | GSTP1 (0.58) | HPGDPTPN1GSTP1 | |
| SCHEMBL28608830 | 0.78 | GSTP1 (0.48) | HPGDPTPN1GSTP1 | |
| SCHEMBL2429223 | 0.76 | TOP1 (0.48) | TOP1CYCS | |
| SCHEMBL26472134 | 0.75 | TERT (0.44) | TOP1CYCS | |
| SCHEMBL1480744 | 0.75 | LMNA (0.55) | HPGDPTPN1SIRT2SIRT1SIRT3 | |
| SCHEMBL16978936 | 0.74 | TOP1 (0.47) | TOP1CYCSSTAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3095183-A | — | — | None | — | — | JP | disclosed |
| JP-H0395183-A | PORPHYRIN DERIVATIVE WITH POLYMERIZABLE GROUP AND ITS PRODUCTION | TOKUYAMA SODA CO LTD | 1991-04-19 | — | — | JP | disclosed |