SCHEMBL2429223

SCHEMBL2429223

C=CCOc1ccc(-c2c3nc(c(-c4ccc(OCC=C)cc4)c4ccc([nH]4)c(-c4ccc(OCC=C)cc4)c4nc(c(-c5ccc(OCC=C)cc5)c5ccc2[nH]5)C=C4)C=C3)cc1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 4/20 0.48
▸ CYCS P99999 3/20 0.47
▸ ABCG2 Q9UNQ0 1/20 0.46
▸ ENPP2 Q13822 1/20 0.46
▸ TERT O14746 4/20 0.46
▸ KDM4E B2RXH2 2/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18510097 0.89 CYCS (0.41) TOP1CYCSABCG2ENPP2TERT
SCHEMBL663652 0.87 TERT (0.41) TOP1CYCSABCG2ENPP2TERT
SCHEMBL6924219 0.83 STAT3 (0.53) TOP1CYCSABCG2ENPP2TERT
SCHEMBL29454950 0.81 TERT (0.55) TOP1CYCSABCG2ENPP2TERT
SCHEMBL18518628 0.81 ADORA2A (0.37) TOP1CYCSABCG2ENPP2TERT
SCHEMBL21919661 0.79 LMNA (0.39) TOP1KDM4EMAPT
SCHEMBL31169674 0.78 TERT (0.50) TOP1CYCSABCG2ENPP2TERT
SCHEMBL28355568 0.78 TOP1 (0.49) TOP1CYCSABCG2ENPP2TERT
SCHEMBL9315040 0.78 TOP1 (0.51) TOP1CYCSABCG2ENPP2TERT
SCHEMBL16978969 0.77 TERT (0.49) TOP1CYCSABCG2ENPP2TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11753551-B2 Stable organic light emitting coating YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. 2023-09-12 — — US disclosed
US-20210071014-A1 STABLE ORGANIC LIGHT EMITTING COATING RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2021-03-11 — — US disclosed
US-10253251-B2 Nanomatrix separation of chromophores and uses thereof in luminescent devices RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2019-04-09 — — US disclosed
US-9693720-B2 Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement MEDTRONIC MINIMED, INC. (US) 2017-07-04 — — US disclosed
US-20150080685-A1 EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT MEDTRONIC MINIMED, INC. (US) 2015-03-19 — — US disclosed
US-20150079423-A1 NANOMATRIX SEPARATION OF CHROMOPHORES AND USES THEREOF IN LUMINESCENT DEVICES RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2015-03-19 — — US disclosed
US-8983565-B2 Optical determination of pH and glucose MEDTRONIC MINIMED, INC. (US) 2015-03-17 — — US disclosed
US-8917018-B2 Nanomatrix separation of chromophores and uses thereof in luminescent devices RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2014-12-23 — — US disclosed
US-8738107-B2 Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement MEDTRONIC MINIMED, INC. (US) 2014-05-27 — — US disclosed
EP-2122361-B1 OPTICAL DETERMINATION OF PH AND GLUCOSE GLUMETRICS INC (US) 2014-03-12 — — EP disclosed
US-20090018418-A1 EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT GLUMETRICS, INC. (US) 2009-01-15 — — US disclosed
US-20080299664-A1 Reagent For Lead Assay KOWA CO., LTD. (JP) 2008-12-04 — — US disclosed
US-20080299664-A1 Reagent For Lead Assay KOWA CO., LTD. (JP) 2008-12-04 — — US disclosed
US-20080299664-A1 Reagent For Lead Assay KOWA CO., LTD. (JP) 2008-12-04 — — US disclosed
WO-2008141241-A1 EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT GLUMETRICS, INC. (US) 2008-11-20 — — WO disclosed
US-20080188722-A1 OPTICAL DETERMINATION OF PH AND GLUCOSE MEDTRONIC MINIMED, INC. 2008-08-07 — — US disclosed
EP-1772730-A1 REAGENT FOR LEAD ASSAY Kowa Co., Ltd. (JP) 2007-04-11 — — EP disclosed
EP-1772730-A1 REAGENT FOR LEAD ASSAY Kowa Co., Ltd. (JP) 2007-04-11 — — EP disclosed
EP-1574531-A1 METHOD OF DETERMINING TRACE METAL Kowa Co., Ltd. (JP) 2005-09-14 — — EP disclosed
US-6437067-B1 Porphyrin-nucleus introduced polymers KOWA CO., LTD. (JP) 2002-08-20 — — US disclosed
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