Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225741 | 1.00 | NPC1 (0.50) | NPC1RAB9AHPGDALDH1A1MAPT | |
| SCHEMBL11409022 | 0.98 | NPC1 (0.48) | NPC1RAB9AHPGDALDH1A1MAPT | |
| SCHEMBL4776892 | 0.82 | KEAP1 (0.52) | NPC1RAB9AALDH1A1MAPTHTT | |
| SCHEMBL8763290 | 0.82 | ALDH1A1 (0.57) | NPC1RAB9AALDH1A1MAPTHTT | |
| SCHEMBL30527294 | 0.82 | ALDH1A1 (0.57) | NPC1RAB9AALDH1A1MAPTHTT | |
| SCHEMBL12882520 | 0.81 | GAA (0.41) | NPC1RAB9AHPGDALDH1A1MAPT | |
| SCHEMBL9840547 | 0.80 | TSHR (0.39) | NPC1RAB9AHPGDALDH1A1MAPT | |
| SCHEMBL13257963 | 0.80 | NPC1 (0.54) | NPC1RAB9AHPGDALDH1A1MAPT | |
| SCHEMBL13412750 | 0.79 | ALDH1A1 (0.50) | NPC1RAB9AHPGDALDH1A1MAPT | |
| SCHEMBL9685869 | 0.79 | TSHR (0.38) | NPC1RAB9AHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072664-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TOPBP1-BRCT7/8 THAT EXERT ANTI-MYC ACTIVITY AND SYNERGY WITH INHIBITORS OF PARP1/2 AND PARP14 | BAYLOR COLLEGE OF MEDICINE (US) | 2025-04-03 | — | — | WO | disclosed |
| US-5025096-A | Preparation of indole and indole derivatives | MINE SAFETY APPLIANCES COMPANY (US) | 1991-06-18 | — | — | US | disclosed |
| EP-0026040-B1 | SUBSTITUTED BENZOPHENONE HYDRAZONES, PESTICIDAL COMPOSITIONS CONTAINING THEM AND METHOD OF COMBATING PESTS | FBC LIMITED (GB) | 1985-03-13 | — | — | EP | disclosed |
| US-4097599-A | PESTICIDES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1978-06-27 | — | — | US | disclosed |
| US-4038405-A | MITICIDES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1977-07-26 | — | — | US | disclosed |