SCHEMBL28938366

SCHEMBL28938366

C=C(C)C(=O)OOC(=O)c1ccccc1C(=O)OC

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.51
POLB P06746 1/20 0.51
ATM Q13315 1/20 0.51
LMNA P02545 3/20 0.50
TSHR P16473 2/20 0.50
ALDH1A1 P00352 4/20 0.49
HSD17B10 Q99714 2/20 0.49
CFTR P13569 1/20 0.49
GLA P06280 1/20 0.45
KMT2A Q03164 2/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA5A P35218 1/20 0.44
CA9 Q16790 1/20 0.44
MAPT P10636 1/20 0.44
ALOX15 P16050 1/20 0.44
SLC6A3 Q01959 3/20 0.42
MYC P01106 1/20 0.42
SLC6A4 P31645 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30125534 1.00 KDM4E (0.51) KDM4EPOLBATMLMNATSHR
SCHEMBL21271559 0.86 ALDH1A1 (0.48) KDM4ELMNATSHRALDH1A1HSD17B10
SCHEMBL23152384 0.85 TSHR (0.65) KDM4EPOLBATMLMNATSHR
SCHEMBL8453228 0.83 NPC1 (0.43) LMNATSHRKMT2AMAPT
SCHEMBL9643500 0.82 ELANE (0.53) POLBATMLMNAALDH1A1KMT2A
SCHEMBL9801403 0.82 NPC1 (0.47) KDM4ELMNATSHRALDH1A1HSD17B10
SCHEMBL30730734 0.82 TSHR (0.66) KDM4ELMNATSHRALDH1A1HSD17B10
SCHEMBL466072 0.82 TSHR (0.66) KDM4ELMNATSHRALDH1A1HSD17B10
SCHEMBL11760962 0.80 LMNA (0.59) KDM4EPOLBATMLMNATSHR
SCHEMBL4925153 0.79 SLC6A3 (0.63) KDM4EPOLBATMLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115461405-A Composition, transfer sheet, melamine decorative sheet, and method for producing melamine decorative sheet 爱克工业株式会社 2022-12-09 CN disclosed