Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9801326 | 0.82 | KMT2A (0.46) | KMT2AMEN1TDP1PLAAT3PLAAT5 | |
| SCHEMBL454778 | 0.81 | PLAAT3 (0.51) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10423547 | 0.75 | CYP3A4 (0.47) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL11076794 | 0.74 | PLAAT3 (0.45) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL12040762 | 0.74 | HPGD (0.51) | KMT2AMEN1TDP1ALDH1A1KDM4E | |
| SCHEMBL10454536 | 0.74 | IAPP (0.59) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL2223565 | 0.73 | PPARA (0.49) | KMT2AMEN1TDP1PLAAT3PLAAT5 | |
| SCHEMBL11569485 | 0.73 | ALDH1A1 (0.44) | KMT2AMEN1TDP1PLAAT3PLAAT5 | |
| SCHEMBL3839694 | 0.72 | IAPP (0.58) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL2125187 | 0.71 | HDAC3 (0.51) | PLAAT3PLAAT5PLAAT2PLAAT4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999440-A | Phenylethyloxirane Intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0291795-B1 | HYDROXYALKYL TRIAZOLYL DERIVATIVES | BAYER AG (DE) | 1990-12-05 | — | — | EP | disclosed |
| US-4894383-A | Fungicidal hydroxyalkyl-triazolyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-16 | — | — | US | disclosed |
| EP-0291795-A2 | Hydroxyalkyl triazolyl derivatives | BAYER AG (DE) | 1988-11-23 | — | — | EP | disclosed |