SCHEMBL140668

SCHEMBL140668

CO[SiH](CCNc1ccccc1)OC

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.50
ALDH1A1 P00352 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.44
GAA P10253 1/20 0.41
KCNH3 Q9ULD8 3/20 0.38
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HTT P42858 1/20 0.35
POLB P06746 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
ICMT O60725 1/20 0.35
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15063443 0.89 MAPT (0.57) MAPTALDH1A1L3MBTL1GAAKCNH3
SCHEMBL49468 0.87 MAPT (0.55) MAPTALDH1A1L3MBTL1GAAKCNH3
SCHEMBL25403652 0.85 MAPT (0.53) MAPTALDH1A1L3MBTL1GAAKCNH3
SCHEMBL15361090 0.85 MAPT (0.53) MAPTALDH1A1L3MBTL1GAAKCNH3
SCHEMBL18496782 0.81 MAPT (0.44) MAPTALDH1A1L3MBTL1GAACYP3A4
SCHEMBL774108 0.81 MAPT (0.47) MAPTALDH1A1L3MBTL1GAAKCNH3
SCHEMBL980165 0.79 MAPT (0.43) MAPTALDH1A1L3MBTL1KCNH3CYP1A2
SCHEMBL25269034 0.78 MAPT (0.41) MAPTALDH1A1L3MBTL1GAAKCNH3
SCHEMBL5394816 0.77 ALDH1A1 (0.42) MAPTALDH1A1L3MBTL1GAACYP3A4
SCHEMBL28324270 0.76 MAPT (0.50) MAPTALDH1A1L3MBTL1GAAKCNH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250326910-A1 METHOD FOR PRODUCING SURFACE-MODIFIED MICRO-FIBRILLATED CELLULOSE DÄTWYLER SCHWEIZ AG (CH) 2025-10-23 US claimed
US-20250197703-A1 Chemical Mechanical Planarization Using Amino-Polyorganosiloxane-Coated Abrasives VERSUM MATERIALS US, LLC 2025-06-19 US claimed
WO-2025097879-A1 SINGLE-ENDED POLYFUNCTIONAL STYRENE-CONJUGATED DIENE POLYMER, PREPARATION METHOD THEREFOR, AND USE THEREOF 中国石油天然气股份有限公司 2025-05-15 WO claimed
EP-4532567-A1 METHOD FOR PRODUCING SURFACE-MODIFIED MICRO-FIBRILLATED CELLULOSE Dätwyler Schweiz AG (CH) 2025-04-09 EP claimed
EP-4493635-A1 CHEMICAL MECHANICAL PLANARIZATION USING AMINO-POLYORGANOSILOXANE-COATED ABRASIVES Versum Materials US, LLC (US) 2025-01-22 EP claimed
US-11975091-B2 Composition for enhancing protein strength LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2024-05-07 US claimed
WO-2024010846-A2 CARBON DISULFIDE TREATED MATERIALS AND METHODS OF PURIFYING FLUIDS USING THE SAME ZENITH PURIFICATION, LLC (US) 2024-01-11 WO claimed
WO-2023225764-A1 METHOD FOR PRODUCING SURFACE-MODIFIED MICRO-FIBRILLATED CELLULOSE DÄTWYLER SCHWEIZ AG (CH) 2023-11-30 WO claimed
US-20230324267-A1 DEVICE FOR REDUCING THE VOLUME OF A SAMPLE, A KIT COMPRISING THE SAME, AND USES THEREOF CHUNG YUAN CHRISTIAN UNIVERSITY (TW) 2023-10-12 US claimed
WO-2023178286-A1 CHEMICAL MECHANICAL PLANARIZATION USING AMINO-POLYORGANOSILOXANE-COATED ABRASIVES MERCK PATENT GMBH (DE) 2023-09-21 WO claimed
US-8536294-B2 Adhesive composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-09-17 US claimed
US-20120055105-A1 ADHESIVES AND SEALANTS BASED ON SILANE-TERMINATED BINDERS FOR BONDING AND SEALING FLEXIBLE SOLAR FILMS/PHOTOVOLTAIC MODULES HENKEL AG & CO. KGAA (DE) 2012-03-08 US claimed
EP-1735369-B1 FAST CURING POLYDIORGANOSILOXANES HENKEL AG & CO KGAA (DE) 2008-12-03 EP claimed
US-20070135601-A1 Initiator systems for polymerisable compositions HUNTSMAN ADVANCED MATERIALS AMERICAS INC. (US) 2007-06-14 US claimed
JP-2007510788-A 2007-04-26 JP claimed
EP-1735369-A1 FAST CURING POLYDIORGANOSILOXANES Henkel Kommanditgesellschaft auf Aktien (DE) 2006-12-27 EP claimed
EP-1685165-A1 INITIATOR SYSTEMS FOR POLYMERISABLE COMPOSITIONS Huntsman Advanced Materials (Switzerland) GmbH (CH) 2006-08-02 EP claimed
WO-2005100446-A1 FAST CURING POLYDIORGANOSILOXANES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-10-27 WO claimed
US-20050234208-A1 Fast curing polydiorganosiloxanes HENKEL AG & CO. KGAA (DE) 2005-10-20 US claimed
WO-2005044867-A1 INITIATOR SYSTEMS FOR POLYMERISABLE COMPOSITIONS HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2005-05-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135601-A1 Initiator systems for polymerisable compositions PFAS, PTK2, PNN MAPT 1447/4885ALDH1A1 2675/4885L3MBTL1 3161/4885
US-11975091-B2 Composition for enhancing protein strength CUTA, S100A4, S100A8 MAPT 1134/4885ALDH1A1 4181/4885L3MBTL1 2049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.