SCHEMBL49468

SCHEMBL49468

CO[SiH](CCCCNc1ccccc1)OC

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.55
ALDH1A1 P00352 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.40
KCNH3 Q9ULD8 3/20 0.39
PPARG P37231 1/20 0.38
GAA P10253 2/20 0.37
BCHE P06276 2/20 0.37
ACHE P22303 2/20 0.37
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
NCOR2 Q9Y618 1/20 0.36
CHRM2 P08172 1/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25403652 0.98 MAPT (0.53) MAPTALDH1A1L3MBTL1KCNH3PPARG
SCHEMBL15361090 0.98 MAPT (0.53) MAPTALDH1A1L3MBTL1KCNH3PPARG
SCHEMBL15063443 0.95 MAPT (0.57) MAPTALDH1A1L3MBTL1KCNH3PPARG
SCHEMBL18496782 0.90 MAPT (0.44) MAPTALDH1A1L3MBTL1GAABCHE
SCHEMBL140668 0.87 MAPT (0.50) MAPTALDH1A1L3MBTL1KCNH3GAA
SCHEMBL3200243 0.83 GAA (0.61) MAPTALDH1A1L3MBTL1PPARGGAA
SCHEMBL722359 0.83 ALDH1A1 (0.52) MAPTALDH1A1L3MBTL1KCNH3PPARG
SCHEMBL25403135 0.81 ALDH1A1 (0.50) MAPTALDH1A1L3MBTL1KCNH3BCHE
SCHEMBL15360416 0.81 ALDH1A1 (0.50) MAPTALDH1A1L3MBTL1KCNH3BCHE
SCHEMBL25269034 0.80 MAPT (0.41) MAPTALDH1A1L3MBTL1KCNH3PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240392073-A1 CROSSLINKABLE MASSES BASED ON ORGANYLOXY-GROUP-CONTAINING ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2024-11-28 US claimed
EP-4370597-A1 CROSSLINKABLE MASSES BASED ON ORGANYLOXY-GROUP-CONTAINING ORGANOPOLYSILOXANES Wacker Chemie AG (DE) 2024-05-22 EP claimed
US-20230324267-A1 DEVICE FOR REDUCING THE VOLUME OF A SAMPLE, A KIT COMPRISING THE SAME, AND USES THEREOF CHUNG YUAN CHRISTIAN UNIVERSITY (TW) 2023-10-12 US claimed
WO-2023072376-A1 CROSSLINKABLE MASSES BASED ON ORGANYLOXY-GROUP-CONTAINING ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2023-05-04 WO claimed
CN-110546206-B Crosslinkable substances based on organopolysiloxanes containing organyloxy groups 瓦克化学股份公司 2022-05-24 CN claimed
US-11319444-B2 Cross-linkable masses based on organopolysiloxanes comprising organyloxy groups WACKER CHEMIE AG (DE) 2022-05-03 US claimed
US-20210122920-A1 CROSS-LINKABLE MASSES BASED ON ORGANOPOLYSILOXANES COMPRISING ORGANYLOXY GROUPS WACKER CHEMIE AG (DE) 2021-04-29 US claimed
EP-3565857-B1 CROSS-LINKABLE MASSES BASED ON ORGANOPOLYSILOXANES COMPRISING ORGANYLOXY GROUPS WACKER CHEMIE AG (DE) 2020-03-25 EP claimed
CN-110546206-A crosslinkable substances based on organopolysiloxanes containing organyloxy groups WACKER CHEMIE AG 2019-12-06 CN claimed
US-8709959-B2 Puncture resistant fabric KIMBERLY-CLARK WORLDWIDE, INC. (US) 2014-04-29 US claimed
US-20070048349-A1 Surface-modified medical devices and methods of making BAUSCH & LOMB INCORPORATED 2007-03-01 US claimed
WO-2026105851-A1 SURFACE-TREATED STEEL MATERIAL AND SURFACE-TREATED MEMBER 日本製鉄株式会社 2026-05-21 WO disclosed
EP-4047051-B1 COMPOSITION FOR ENCAPSULANT FILM COMPRISING ETHYLENE/ALPHA-OLEFIN COPOLYMER AND ENCAPSULANT FILM COMPRISING THE SAME LG CHEMICAL LTD (KR) 2026-05-20 EP disclosed
US-12605142-B2 Material for acoustic matching layer, acoustic matching sheet, acoustic wave probe, ultrasound probe, acoustic wave measurement apparatus, ultrasound diagnostic apparatus, and method for manufacturing acoustic wave probe FUJIFILM CORPORATION (JP) 2026-04-21 US disclosed
US-12584015-B2 Polyimide resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-03-24 US disclosed
EP-0423334-B1 RESIN COMPOSITION AND PROCESS FOR FORMING TRANSPARENT THIN FILM NIPPON KAYAKU KK (JP) 1996-09-18 EP disclosed
EP-0696621-A1 COATING COMPOSITION AND SURFACE-COATED MOLDING PRODUCED THEREWITH MITSUBISHI RAYON CO., LTD. (JP) 1996-02-14 EP disclosed
US-5180794-A Resin compositions and process for forming transparent thin films NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1993-01-19 US disclosed
EP-0423334-A1 RESIN COMPOSITION AND PROCESS FOR FORMING TRANSPARENT THIN FILM NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1991-04-24 EP disclosed
US-4927951-A (METH)ACRYLAMIDE GROUP CONTAINING SILOXANES TOSHIBA SILICONE CO., LTD. (JP) 1990-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584015-B2 Polyimide resin composition PSMA1, SEM1, RIF1 MAPT 971/4885ALDH1A1 1879/4885L3MBTL1 2434/4885
US-12605142-B2 Material for acoustic matching layer, acoustic matching sheet, acoustic wave probe, ultrasound probe, acoustic wave measurement apparatus, ultrasound diagnostic apparatus, and method for manufacturing acoustic wave probe PIEZO1, TEX10, ACTN4 MAPT 3941/4885ALDH1A1 902/4885L3MBTL1 1517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.