SCHEMBL9801716

SCHEMBL9801716

CCCN1CCOC(C)C1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 8/20 0.49
KDM1A O60341 1/20 0.48
PDK1 Q15118 1/20 0.43
DRD1 P21728 1/20 0.43
EBP Q15125 1/20 0.41
SIGMAR1 Q99720 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26972530 1.00 DRD3 (0.49) DRD3KDM1APDK1DRD1EBP
SCHEMBL24508777 1.00 DRD3 (0.49) DRD3KDM1APDK1DRD1EBP
SCHEMBL22463774 0.88 SIGMAR1 (0.52) DRD3KDM1APDK1DRD1EBP
SCHEMBL14027741 0.88 SIGMAR1 (0.52) DRD3KDM1APDK1DRD1EBP
SCHEMBL29645051 0.88 SIGMAR1 (0.52) DRD3KDM1APDK1DRD1EBP
SCHEMBL22463763 0.86 EBP (0.59) DRD3KDM1APDK1DRD1EBP
SCHEMBL22463780 0.85 EBP (0.62) DRD3KDM1ADRD1EBPSIGMAR1
SCHEMBL4242387 0.85 EBP (0.62) DRD3KDM1ADRD1EBPSIGMAR1
SCHEMBL6712360 0.85 EBP (0.62) DRD3KDM1ADRD1EBPSIGMAR1
SCHEMBL6833201 0.85 EBP (0.62) DRD3KDM1ADRD1EBPSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3227234-B1 SILICOALUMINOPHOSPHATE MOLECULAR SIEVES USING AN ORGANO-1-OXA-4-AZONIUMCYCLOHEXANE COMPOUND UOP LLC (US) 2021-05-26 EP claimed
US-20180258058-A1 ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS UOP LLC (US) 2018-09-13 US claimed
US-9815706-B2 Zeolites using an organo-1-oxa-4-azoniumcyclohexane compound UOP LLC (US) 2017-11-14 US claimed
EP-3227266-A2 ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS UOP LLC (US) 2017-10-11 EP claimed
US-9751772-B2 Aluminophosphate molecular sieves using an organo-1-oxa-4-azoniumcyclohexane compound UOP LLC (US) 2017-09-05 US claimed
US-20170044120-A1 ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS UOP LLC (US) 2017-02-16 US claimed
US-9522896-B2 Organo-1-oxa-4-azonium cyclohexane compounds UOP LLC (US) 2016-12-20 US claimed
US-20160159656-A1 ALUMINOPHOSPHATE MOLECULAR SIEVES USING AN ORGANO-1-OXA-4-AZONIUMCYCLOHEXANE COMPOUND UOP LLC 2016-06-09 US claimed
US-20160159760-A1 ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS UOP LLC 2016-06-09 US claimed
US-20160159655-A1 ZEOLITES USING AN ORGANO-1-OXA-4-AZONIUMCYCLOHEXANE COMPOUND UOP LLC 2016-06-09 US claimed
US-11858940-B2 Selective modulators of mutant LRRK2 proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2024-01-02 US disclosed
US-11858940-B2 Selective modulators of mutant LRRK2 proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2024-01-02 US disclosed
WO-2023066292-A1 TRICYCLIC BORONIC ACID DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 上海济煜医药科技有限公司 2023-04-27 WO disclosed
WO-2022272248-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2022-12-29 WO disclosed
WO-2021226517-A1 AKT3 MODULATORS GEORGIAMUNE LLC (US) 2021-11-11 WO disclosed
WO-2013036684-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS SATORI PHARMACEUTICALS, INC (US) 2013-03-14 WO disclosed
US-20130060013-A1 Compounds useful for treating neurodegenerative disorders SATORI PHARMACEUTICALS, INC. (US) 2013-03-07 US disclosed
US-20110251379-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS SATORI PHARMACEUTICALS, INC. (US) 2011-10-13 US disclosed
WO-2011109657-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS SATORI PHARMACEUTICALS, INC. (US) 2011-09-09 WO disclosed
US-4992150-A Telomer with alpha-olefin;oil and fuel additive NIPPON OIL CO, LTD. (JP) 1991-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160159760-A1 ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS OXSR1, OXER1, OCIAD1 DRD3 937/4885KDM1A 232/4885PDK1 1344/4885
US-20130060013-A1 Compounds useful for treating neurodegenerative disorders SNCA, HTT, CLN6 DRD3 2616/4885KDM1A 3542/4885PDK1 1550/4885
US-11858940-B2 Selective modulators of mutant LRRK2 proteolysis and associated methods of use LRRK2, ADRM1, CRBN DRD3 3416/4885KDM1A 1766/4885PDK1 1358/4885
US-20180258058-A1 ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS OXSR1, OXER1, OCIAD1 DRD3 937/4885KDM1A 232/4885PDK1 1344/4885
US-20110251379-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS CLN6, NLN, ACHE DRD3 2733/4885KDM1A 2863/4885PDK1 1982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.