Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4872313 | 0.84 | ESR1 (0.46) | ESR1ESR2ALDH1A1CYP3A4TRPA1 | |
| SCHEMBL9774408 | 0.84 | ESR1 (0.58) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL8827949 | 0.80 | ALDH1A1 (0.48) | ESR1ESR2ALDH1A1CYP3A4TRPA1 | |
| SCHEMBL985924 | 0.80 | ESR1 (0.44) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL984123 | 0.79 | ESR1 (0.48) | ESR1ESR2ALDH1A1CYP3A4TRPA1 | |
| SCHEMBL8370433 | 0.78 | ESR1 (0.41) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL982152 | 0.78 | ESR1 (0.42) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL1253793 | 0.78 | ESR1 (0.56) | ESR1ESR2ALDH1A1CYP3A4TRPA1 | |
| SCHEMBL984765 | 0.77 | ESR1 (0.41) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL2201035 | 0.76 | ESR1 (0.46) | ESR1ESR2ALDH1A1CYP3A4TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275405-B1 | PROCESS FOR PRODUCING ISOCYANATE USING DIARYL CARBONATE | ASAHI CHEMICAL IND (JP) | 2019-04-24 | — | — | EP | disclosed |
| EP-2275406-B1 | PROCESS FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2018-11-28 | — | — | EP | disclosed |
| EP-2792673-B1 | Carbamic acid ester derivatives for the production of isocyanate and aromatic hydroxy compounds | ASAHI CHEMICAL IND (JP) | 2018-07-25 | — | — | EP | disclosed |
| US-9637445-B2 | Isocyanate production process using composition containing carbamic acid ester and aromatic hydroxy compound, and composition for transfer and storage of carbamic acid ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2017-05-02 | — | — | US | disclosed |
| EP-2147909-B1 | METHOD FOR PRODUCTION OF ISOCYANATE USING COMPOSITION COMPRISING CARBAMIC ACID ESTER AND AROMATIC HYDROXY COMPOUND, AND COMPOSITION FOR TRANSPORT OR STORAGE OF CARBAMIC ACID ESTER | ASAHI CHEMICAL IND (JP) | 2016-12-14 | — | — | EP | disclosed |
| US-9233918-B2 | Isocyanate production process | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-01-12 | — | — | US | disclosed |
| CN-103467730-B | Carbamate compounds | Asahi Kasei Chemical K. K. (JP) | 2015-12-23 | — | — | CN | disclosed |
| US-20150259279-A1 | Isocyanate Production Process Using Composition Containing Carbamic Acid Ester and Aromatic Hydroxy Compound, and Composition for Transfer and Storage of Carbamic Acid Ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-09-17 | — | — | US | disclosed |
| EP-2213658-B1 | METHOD FOR PRODUCTION OF ISOCYANATE AND AROMATIC HYDROXY COMPOUND | ASAHI KASEI CHEMICALS CORP (JP) | 2015-09-09 | — | — | EP | disclosed |
| US-9056819-B2 | Isocyanate production process using composition containing carbamic acid ester and aromatic hydroxy compound, and composition for transfer and storage of carbamic acid ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-06-16 | — | — | US | disclosed |
| US-20110319648-A1 | Isocyanates and Aromatic Hydroxy Compounds | SHINOHATA MASAAKI (JP) | 2011-12-29 | — | — | US | disclosed |
| US-7977504-B2 | Process for producing isocyanates and aromatic hydroxy compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20110092731-A1 | ISOCYANATE PRODUCTION PROCESS | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| US-20110054211-A1 | PROCESS FOR PRODUCING ISOCYANATES USING DIARYL CARBONATE | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-03-03 | — | — | US | disclosed |
| EP-2275406-A1 | PROCESS FOR PRODUCING ISOCYANATE | Asahi Kasei Chemicals Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |
| EP-2275405-A1 | PROCESS FOR PRODUCING ISOCYANATE USING DIARYL CARBONATE | Asahi Kasei Chemicals Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-20100274047-A1 | PROCESS FOR PRODUCING OF ISOCYANATES AND AROMATIC HYDROXY COMPOUNDS | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-10-28 | — | — | US | disclosed |
| EP-2213658-A1 | METHOD FOR PRODUCTION OF ISOCYANATE AND AROMATIC HYDROXY COMPOUND | Asahi Kasei Chemicals Corporation (JP) | 2010-08-04 | — | — | EP | disclosed |
| US-20100113823-A1 | ISOCYANATE PRODUCTION PROCESS USING COMPOSITION CONTAINING CARBAMIC ACID ESTER AND AROMATIC HYDROXY COMPOUND, AND COMPOSITION FOR TRANSFER AND STORAGE OF CARBAMIC ACID ESTER | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-05-06 | — | — | US | disclosed |
| EP-2147909-A1 | METHOD FOR PRODUCTION OF ISOCYANATE USING COMPOSITION COMPRISING CARBAMIC ACID ESTER AND AROMATIC HYDROXY COMPOUND, AND COMPOSITION FOR TRANSPORT OR STORAGE OF CARBAMIC ACID ESTER | Asahi Kasei Chemicals Corporation (JP) | 2010-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113823-A1 | ISOCYANATE PRODUCTION PROCESS USING COMPOSITION CONTAINING CARBAMIC ACID ESTER AND AROMATIC HYDROXY COMPOUND, AND COMPOSITION FOR TRANSFER AND STORAGE OF CARBAMIC ACID ESTER | PAH, APEH, CPS1 | ESR1 1799/4885ESR2 2808/4885ALDH1A1 2908/4885 |
| US-20110319648-A1 | Isocyanates and Aromatic Hydroxy Compounds | PAH, APEH, HPD | ESR1 818/4885ESR2 1554/4885ALDH1A1 2817/4885 |
| US-20110092731-A1 | ISOCYANATE PRODUCTION PROCESS | CPS1, PHGDH, APEH | ESR1 3842/4885ESR2 3685/4885ALDH1A1 2204/4885 |
| US-20110054211-A1 | PROCESS FOR PRODUCING ISOCYANATES USING DIARYL CARBONATE | PAH, AADAC, PHGDH | ESR1 3192/4885ESR2 3093/4885ALDH1A1 3223/4885 |
| US-20100274047-A1 | PROCESS FOR PRODUCING OF ISOCYANATES AND AROMATIC HYDROXY COMPOUNDS | PAH, APEH, HPD | ESR1 1124/4885ESR2 1539/4885ALDH1A1 2913/4885 |
| US-20150259279-A1 | Isocyanate Production Process Using Composition Containing Carbamic Acid Ester and Aromatic Hydroxy Compound, and Composition for Transfer and Storage of Carbamic Acid Ester | PAH, APEH, CPS1 | ESR1 1799/4885ESR2 2808/4885ALDH1A1 2908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.