Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17684717 | 0.74 | HTR2C (0.45) | KDM1ARCOR1HTR2CDRD2HTR1A | |
| SCHEMBL11466477 | 0.72 | HCAR3 (0.41) | KDM1AHTR2CGUSBLMNACES2 | |
| SCHEMBL10515985 | 0.72 | CHRNA7 (0.44) | KDM1ACHRM2 | |
| SCHEMBL10518769 | 0.70 | KDM1A (0.49) | KDM1ACES2MGLL | |
| SCHEMBL9516589 | 0.70 | KDM1A (0.45) | KDM1ARCOR1HTR2CDRD2GUSB | |
| SCHEMBL9516595 | 0.70 | KDM1A (0.45) | KDM1ARCOR1HTR2CDRD2GUSB | |
| SCHEMBL11466479 | 0.69 | KDM1A (0.38) | KDM1ARCOR1HTR2CDRD2HTR1A | |
| Methyl Alcohol SCHEMBL9419583 | 0.69 | TSHR (0.58) | HTR2CHTR2BHTR2ACES2MGLL | |
| SCHEMBL8090368 | 0.68 | GUSB (0.45) | KDM1ARCOR1HTR2CGUSBLMNA | |
| SCHEMBL6492774 | 0.68 | HTR1A (0.62) | KDM1ARCOR1HTR2CDRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228045-B1 | AROMATIC THIOETHERS | CIBA-GEIGY AG (CH) | 1991-04-03 | — | — | EP | disclosed |
| US-4785004-A | ANTIALLERGENS, ANTIHISTAMINES | CIBA-GEIGY CORPORATION (US) | 1988-11-15 | — | — | US | disclosed |
| EP-0228045-A2 | Aromatic thioethers | CIBA-GEIGY AG (CH) | 1987-07-08 | — | — | EP | disclosed |