Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 5/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29827335 | 1.00 | PDE2A (0.50) | PDE2AIDO1AHRALDH1A1MAPT | |
| SCHEMBL30326145 | 0.81 | PDE2A (0.46) | PDE2AIDO1AHRALDH1A1MAPT | |
| SCHEMBL5756914 | 0.81 | PDE2A (0.46) | PDE2AIDO1AHRALDH1A1MAPT | |
| SCHEMBL2792621 | 0.80 | PDE2A (0.45) | PDE2AALDH1A1MAPT | |
| SCHEMBL29402881 | 0.80 | TSHR (0.61) | PDE2AAHRALDH1A1MAPTMCL1 | |
| SCHEMBL980201 | 0.80 | TSHR (0.61) | PDE2AAHRALDH1A1MAPTMCL1 | |
| SCHEMBL530151 | 0.79 | HTT (0.42) | ALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL28020319 | 0.78 | TSHR (0.58) | PDE2AAHRALDH1A1MAPTMCL1 | |
| SCHEMBL19785361 | 0.78 | PDE2A (0.52) | PDE2AAHRALDH1A1MAPTHSD11B1 | |
| SCHEMBL29827588 | 0.77 | PDE2A (0.50) | PDE2AIDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431162-A | Preparation method of flufenoxuron intermediate | 浙江工业大学 | 2025-02-14 | — | — | CN | claimed |
| CN-113896611-B | Preparation method of 3-chloro-4-fluorobenzotrifluoride | 浙江工业大学 | 2024-02-13 | — | — | CN | claimed |
| CN-217120226-U | Production system of isoxazole compound | 内蒙古蓝科生物科技有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-113896611-A | Preparation method of 3-chloro-4-fluorobenzotrifluoride | 浙江工业大学 | 2022-01-07 | — | — | CN | claimed |
| CN-212915629-U | Reaction device for 3-chloro-4-fluorobenzotrifluoride | 浙江华基生物技术有限公司 | 2021-04-09 | — | — | CN | claimed |
| US-8642802-B2 | Process for the preparation of halogenated benzoic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2014-02-04 | — | — | US | claimed |
| EP-2310349-B1 | PROCESS FOR THE PREPARATION OF HALOGENATED BENZOIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2013-04-24 | — | — | EP | claimed |
| US-20120330055-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED BENZOIC ACID DERIVATIVES | BACHMANN STEPHAN (CH) | 2012-12-27 | — | — | US | claimed |
| US-8329939-B2 | Process for the preparation of halogenated benzoic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2012-12-11 | — | — | US | claimed |
| US-20120130121-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED BENZOIC ACID DERIVATIVES | BACHMANN STEPHAN (CH) | 2012-05-24 | — | — | US | claimed |
| EP-0847977-B1 | 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | NIPPON SODA CO (JP) | 2001-08-29 | — | — | EP | claimed |
| EP-0847977-A1 | 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | NIPPON SODA CO., LTD. (JP) | 1998-06-17 | — | — | EP | claimed |
| EP-0560905-B1 | 3-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-1-AZETIDINE CARBOXAMIDES HAVING ANTICONVULSANT ACTIVITY | ROBINS CO INC A H (US) | 1994-10-19 | — | — | EP | claimed |
| US-4603222-A | Method for the preparation of nitrodiphenyl ethers | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-07-29 | — | — | US | claimed |
| EP-0173349-A1 | Method for the preparation of nitrodiphenyl ethers | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-03-05 | — | — | EP | claimed |
| EP-0159388-A2 | Preparation of nuclear chlorinated compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1985-10-30 | — | — | EP | claimed |
| US-4484008-A | SOLVENT EXTRACTION WITH WATER AND SEPARATION | PPG INDUSTRIES, INC. (US) | 1984-11-20 | — | — | US | claimed |
| US-4470930-A | Preparation of nuclear chlorinated aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-11 | — | — | US | claimed |
| US-4469893-A | Method for the preparation of nitrodiphenyl ethers | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-04 | — | — | US | claimed |
| US-4424396-A | ARYL HALIDE, A-AMINOACID | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-01-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120330055-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED BENZOIC ACID DERIVATIVES | CYP2F1, GABRA5, CYP3A5 | PDE2A 4641/4885IDO1 4014/4885AHR 338/4885 |
| US-20120130121-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED BENZOIC ACID DERIVATIVES | CYP2F1, GABRA5, CYP3A5 | PDE2A 4641/4885IDO1 4014/4885AHR 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.