Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 5/20 | 0.42 |
| ▸ | CCKAR | P32238 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9802338 | 1.00 | CCKBR (0.42) | CCKBRCCKARNAMPTMAPTTP53 | |
| SCHEMBL9802345 | 1.00 | CCKBR (0.42) | CCKBRCCKARNAMPTMAPTTP53 | |
| SCHEMBL9802133 | 1.00 | CCKBR (0.42) | CCKBRCCKARNAMPTMAPTTP53 | |
| SCHEMBL9802246 | 0.90 | PYGL (0.41) | CCKBRNAMPTNPY1R | |
| SCHEMBL9802851 | 0.90 | PYGL (0.41) | CCKBRNAMPTNPY1R | |
| SCHEMBL9802229 | 0.90 | PYGL (0.41) | CCKBRNAMPTNPY1R | |
| SCHEMBL9802866 | 0.90 | PYGL (0.41) | CCKBRNAMPTNPY1R | |
| SCHEMBL9802184 | 0.89 | PYGL (0.41) | CCKBRNAMPTMEN1KMT2A | |
| SCHEMBL9802276 | 0.89 | PYGL (0.41) | CCKBRNAMPTMEN1KMT2A | |
| SCHEMBL9802171 | 0.89 | PYGL (0.41) | CCKBRNAMPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055464-A | Cognition activators, diuretics, antiulcer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0322779-A2 | Benzolactam compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |