Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 7/20 | 0.37 |
| ▸ | MME | P08473 | 3/20 | 0.37 |
| ▸ | CCKBR | P32239 | 2/20 | 0.36 |
| ▸ | BCL2L11 | O43521 | 2/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9802866 | 1.00 | PYGL (0.41) | PYGLACEMMECCKBRBCL2L11 | |
| SCHEMBL9802246 | 1.00 | PYGL (0.41) | PYGLACEMMECCKBRBCL2L11 | |
| SCHEMBL9802851 | 1.00 | PYGL (0.41) | PYGLACEMMECCKBRBCL2L11 | |
| SCHEMBL9802133 | 0.90 | CCKBR (0.42) | CCKBRNAMPTNPY1R | |
| SCHEMBL9802345 | 0.90 | CCKBR (0.42) | CCKBRNAMPTNPY1R | |
| SCHEMBL9802125 | 0.90 | CCKBR (0.42) | CCKBRNAMPTNPY1R | |
| SCHEMBL9802338 | 0.90 | CCKBR (0.42) | CCKBRNAMPTNPY1R | |
| SCHEMBL9802171 | 0.90 | PYGL (0.41) | PYGLACEMMECCKBRNAMPT | |
| SCHEMBL9802290 | 0.90 | PYGL (0.41) | PYGLACEMMECCKBRNAMPT | |
| SCHEMBL9802276 | 0.90 | PYGL (0.41) | PYGLACEMMECCKBRNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055464-A | Cognition activators, diuretics, antiulcer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0322779-A2 | Benzolactam compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |