Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11606834 | 0.79 | ALDH1A1 (0.60) | POLBALDH1A1KDM4EMAPTHTT | |
| SCHEMBL11703768 | 0.75 | POLB (0.46) | POLBALDH1A1KDM4EMAPTHTT | |
| Metribuzin SCHEMBL8535922 | 0.75 | HPGD (0.51) | POLBALDH1A1KDM4EMAPTHTT | |
| Metribuzin SCHEMBL66824 | 0.75 | HPGD (0.51) | POLBALDH1A1KDM4EMAPTHTT | |
| SCHEMBL11713346 | 0.74 | POLB (0.63) | POLBALDH1A1KDM4EMAPTHTT | |
| SCHEMBL7029971 | 0.71 | ALDH1A1 (0.55) | POLBALDH1A1KDM4EMAPTHTT | |
| SCHEMBL11716000 | 0.71 | POLB (0.42) | POLBALDH1A1KDM4EMAPTHTT | |
| SCHEMBL11124622 | 0.71 | ALDH1A1 (0.36) | POLBALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9802279 | 0.71 | POLB (0.39) | POLBALDH1A1KDM4EMAPTHTT | |
| SCHEMBL3947756 | 0.70 | ALDH1A1 (1.00) | POLBALDH1A1KDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168766-B1 | PROCESS FOR THE PREPARATION OF S-SUBSTITUTED ISOTHIO UREAS | MOBAY CORPORATION (US) | 1989-08-16 | — | — | EP | disclosed |
| US-4783531-A | Production of S-substituted isothioureas | MOBAY CORPORATION (US) | 1988-11-08 | — | — | US | disclosed |
| US-4659819-A | Production of S-substituted isothioureas | MOBAY CORPORATION (US) | 1987-04-21 | — | — | US | disclosed |
| EP-0168766-A2 | Process for the preparation of S-substituted isothio ureas | MOBAY CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |
| US-4402733-A | PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1983-09-06 | — | — | US | disclosed |
| US-4036632-A | CONTROLLING WEEDS USING 3-METHYLTHIO-4-AMINO-6-BUTYL-1,2,4 TRIAZINE-5-ONE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
| US-3966715-A | 1,2,4-TRIAZINE-5-ONES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |
| US-3961936-A | SUBSTITUTED 1,2,4-TRIAZINE-5-ONES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |