Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CCKAR | P32238 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9802812 | 1.00 | GAA (0.48) | GAASMN1; SMN2NPSR1LMNAMEN1 | |
| SCHEMBL9802457 | 1.00 | GAA (0.48) | GAASMN1; SMN2NPSR1LMNAMEN1 | |
| SCHEMBL9802817 | 1.00 | GAA (0.48) | GAASMN1; SMN2NPSR1LMNAMEN1 | |
| SCHEMBL11314209 | 0.84 | GAA (0.52) | GAASMN1; SMN2NPSR1LMNAMEN1 | |
| SCHEMBL9802149 | 0.84 | SIGMAR1 (0.47) | CYP2C19ALDH1A1 | |
| SCHEMBL9802141 | 0.84 | SIGMAR1 (0.47) | CYP2C19ALDH1A1 | |
| SCHEMBL9802216 | 0.84 | SIGMAR1 (0.47) | CYP2C19ALDH1A1 | |
| SCHEMBL9802776 | 0.84 | SIGMAR1 (0.47) | CYP2C19ALDH1A1 | |
| SCHEMBL9802815 | 0.84 | SIGMAR1 (0.47) | CYP2C19ALDH1A1 | |
| SCHEMBL9040545 | 0.80 | CCKBR (0.45) | GAASMN1; SMN2CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055464-A | Cognition activators, diuretics, antiulcer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0322779-A2 | Benzolactam compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |