Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.42 |
| ▸ | GOT1 | P17174 | 1/20 | 0.42 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.42 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9802149 | 1.00 | SIGMAR1 (0.47) | SIGMAR1CYP2C19PYGLAADATGOT1 | |
| SCHEMBL9802141 | 1.00 | SIGMAR1 (0.47) | SIGMAR1CYP2C19PYGLAADATGOT1 | |
| SCHEMBL9802216 | 1.00 | SIGMAR1 (0.47) | SIGMAR1CYP2C19PYGLAADATGOT1 | |
| SCHEMBL9802815 | 1.00 | SIGMAR1 (0.47) | SIGMAR1CYP2C19PYGLAADATGOT1 | |
| SCHEMBL9802473 | 0.84 | GAA (0.48) | CYP2C19ALDH1A1 | |
| SCHEMBL9802457 | 0.84 | GAA (0.48) | CYP2C19ALDH1A1 | |
| SCHEMBL9802812 | 0.84 | GAA (0.48) | CYP2C19ALDH1A1 | |
| SCHEMBL9802817 | 0.84 | GAA (0.48) | CYP2C19ALDH1A1 | |
| SCHEMBL9802290 | 0.75 | PYGL (0.41) | SIGMAR1PYGL | |
| SCHEMBL9802171 | 0.75 | PYGL (0.41) | SIGMAR1PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055464-A | Cognition activators, diuretics, antiulcer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0322779-A2 | Benzolactam compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |