Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 8/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9802765 | 0.79 | PTK2 (0.47) | PTK2BRD4TSHRL3MBTL1DYRK1A | |
| SCHEMBL23537851 | 0.71 | AR (0.40) | PTK2DYRK1AALDH1A1MAPTHSD17B10 | |
| SCHEMBL15592920 | 0.70 | PTK2 (0.54) | PTK2BRD4TSHRL3MBTL1DYRK1A | |
| SCHEMBL6907631 | 0.70 | PTK2 (0.46) | PTK2BRD4TSHRL3MBTL1LMNA | |
| SCHEMBL9803050 | 0.70 | L3MBTL1 (0.48) | PTK2BRD4TSHRL3MBTL1DYRK1A | |
| SCHEMBL19429469 | 0.69 | PKN1 (0.45) | PTK2BRD4GRIN2DGRIN3BGRIN1 | |
| Pyrrole SCHEMBL9107990 | 0.67 | KCNA5 (0.45) | PTK2BRD4TSHRL3MBTL1DYRK1A | |
| SCHEMBL8525719 | 0.66 | PTK2 (0.65) | PTK2BRD4TSHRL3MBTL1ALOX15 | |
| SCHEMBL9802626 | 0.66 | ALDH1A1 (0.46) | TSHRALDH1A1POLBMAPK1LMNA | |
| SCHEMBL934852 | 0.64 | PTK2 (0.61) | PTK2BRD4TSHRL3MBTL1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068334-A | Analgesics and antipyretics | KARL THOMAE GMBH (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0338228-A2 | Use of quinoline-2,5-diones in a medicament having an analgesic, antipyretic and/or antiphlogistic activity | Dr. Karl Thomae GmbH (DE) | 1989-10-25 | — | — | EP | disclosed |