Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | BUB1 | O43683 | 7/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323294 | 0.78 | ALDH1A1 (0.62) | L3MBTL1KMT2AHTTMAPK1SMN1; SMN2 | |
| SCHEMBL11265654 | 0.74 | BRD4 (0.61) | L3MBTL1KMT2AHTTSMN1; SMN2ALOX15 | |
| SCHEMBL9802765 | 0.73 | PTK2 (0.47) | L3MBTL1MAPK1HPGDALDH1A1ALOX15 | |
| SCHEMBL11394395 | 0.72 | PKN2 (0.72) | L3MBTL1KMT2AMAPK1HPGDALDH1A1 | |
| SCHEMBL4467904 | 0.72 | MAPT (0.49) | L3MBTL1KMT2ABRD4MAPTBUB1 | |
| SCHEMBL9802479 | 0.70 | PTK2 (0.41) | L3MBTL1KMT2AHTTMAPK1SMN1; SMN2 | |
| SCHEMBL4417991 | 0.70 | GSK3B (0.46) | L3MBTL1KMT2ABRD4BUB1DYRK1A | |
| SCHEMBL28902024 | 0.70 | PDE4B (0.49) | L3MBTL1KMT2AHTTHPGDALDH1A1 | |
| SCHEMBL9802957 | 0.70 | AKR1B1 (0.44) | L3MBTL1KMT2AHTTMAPK1SMN1; SMN2 | |
| SCHEMBL23537851 | 0.69 | AR (0.40) | KMT2AHPGDALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068334-A | Analgesics and antipyretics | KARL THOMAE GMBH (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0338228-A2 | Use of quinoline-2,5-diones in a medicament having an analgesic, antipyretic and/or antiphlogistic activity | Dr. Karl Thomae GmbH (DE) | 1989-10-25 | — | — | EP | disclosed |