Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | ACACA | Q13085 | 2/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312490 | 0.88 | HDAC1 (0.41) | HDAC1BRD4CREBBPKDM4AKCNA5 | |
| SCHEMBL9802602 | 0.84 | EPHX2 (0.37) | HDAC1BRD4CREBBPKDM4AKCNA5 | |
| SCHEMBL7446408 | 0.80 | DRD2 (0.35) | HDAC1BRD4CREBBPKDM4AKCNA5 | |
| Hydrochloric Acid SCHEMBL7447474 | 0.79 | DRD2 (0.35) | HDAC1BRD4CREBBPKDM4AKCNA5 | |
| SCHEMBL7315264 | 0.79 | KDM4A (0.36) | HDAC1BRD4CREBBPKDM4AKCNA5 | |
| Hydrochloric Acid SCHEMBL7440751 | 0.71 | KMT2A (0.37) | — | |
| SCHEMBL2573836 | 0.69 | HDAC1 (0.57) | HDAC1KDM4AKCNA5MALT1NAMPT | |
| SCHEMBL12305686 | 0.69 | BRD4 (0.57) | HDAC1BRD4CREBBPKDM4ANAMPT | |
| SCHEMBL12305689 | 0.69 | KCNA5 (0.60) | HDAC1KDM4AKCNA5MALT1NAMPT | |
| SCHEMBL5792738 | 0.68 | KCNA5 (0.52) | HDAC1KDM4AKCNA5MALT1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994486-A | Neurological disorders | ABBOTT LABORATORIES (US) | 1991-02-19 | — | — | US | disclosed |