Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9802613 | 0.84 | NPC1 (0.32) | KDM4ESMN1; SMN2GAARAB9A | |
| SCHEMBL9802835 | 0.84 | HDAC1 (0.40) | KCNA5BRD4CREBBPMALT1KDM4A | |
| SCHEMBL7312490 | 0.79 | HDAC1 (0.41) | KCNA5MEN1KMT2ABRD4CREBBP | |
| SCHEMBL7446408 | 0.79 | DRD2 (0.35) | KCNA5KDM4ELMNAHPGDMEN1 | |
| Hydrochloric Acid SCHEMBL7447474 | 0.79 | DRD2 (0.35) | KCNA5KDM4ELMNAHPGDMEN1 | |
| SCHEMBL7315264 | 0.79 | KDM4A (0.36) | KCNA5KDM4ELMNAHPGDMEN1 | |
| SCHEMBL7447927 | 0.73 | KMT2A (0.38) | KMT2AATM | |
| SCHEMBL7447921 | 0.73 | KMT2A (0.38) | KMT2AATM | |
| Hydrochloric Acid SCHEMBL7440751 | 0.72 | KMT2A (0.37) | KMT2AATM | |
| SCHEMBL9802336 | 0.70 | KDM4E (0.43) | KDM4ELMNAHPGDMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994486-A | Neurological disorders | ABBOTT LABORATORIES (US) | 1991-02-19 | — | — | US | disclosed |