Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9455488 | 0.75 | SRD5A1 (0.46) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL718764 | 0.73 | PIK3CD (0.41) | ALDH1A1GAAMAPTCYP2D6CYP2C9 | |
| SCHEMBL1698550 | 0.72 | SMN1; SMN2 (0.41) | ALDH1A1GAAMAPTCYP2D6CYP2C9 | |
| SCHEMBL11237446 | 0.71 | KDM4E (0.33) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL9803355 | 0.70 | ALDH1A1 (0.40) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL21278138 | 0.68 | PIK3CD (0.41) | ALDH1A1GAAMAPTCYP2D6CYP2C9 | |
| SCHEMBL21500436 | 0.66 | PIK3CD (0.40) | ALDH1A1GAAMAPTCYP2D6CYP2C9 | |
| SCHEMBL9802927 | 0.66 | MGLL (0.42) | KDM4EMAPTCYP2D6CYP2C9CHRM2 | |
| SCHEMBL9802715 | 0.64 | HTT (0.36) | ALDH1A1 | |
| SCHEMBL20936142 | 0.64 | PIK3CD (0.35) | ALDH1A1CYP2D6CYP2C9CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068334-A | Analgesics and antipyretics | KARL THOMAE GMBH (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0338228-A2 | Use of quinoline-2,5-diones in a medicament having an analgesic, antipyretic and/or antiphlogistic activity | Dr. Karl Thomae GmbH (DE) | 1989-10-25 | — | — | EP | disclosed |