Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MC4R | P32245 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803398 | 0.82 | LMNA (0.45) | LMNAALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL10359776 | 0.81 | BCHE (0.42) | HPGDEPHX2MAPK1P2RX7MEN1 | |
| SCHEMBL10701273 | 0.76 | ALDH1A1 (0.43) | TSHRHPGDALDH1A1MC4RUSP2 | |
| SCHEMBL10358817 | 0.66 | TSHR (0.46) | TSHRLMNAHPGDALDH1A1EPHX2 | |
| SCHEMBL30239976 | 0.65 | MC4R (0.74) | TSHRHPGDALDH1A1MC4RUSP2 | |
| SCHEMBL10359171 | 0.64 | — | — | |
| SCHEMBL24011132 | 0.63 | HPGD (0.66) | TSHRHPGDALDH1A1MC4RUSP2 | |
| SCHEMBL29941835 | 0.63 | HPGD (0.66) | TSHRLMNAHPGDALDH1A1MC4R | |
| SCHEMBL13773684 | 0.63 | EPHX1 (0.59) | LMNAHPGDALDH1A1EPHX2P2RX7 | |
| SCHEMBL8998862 | 0.63 | HPGD (0.66) | TSHRLMNAHPGDALDH1A1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992518-A | Heat-resistant adhesives; matrix resins; dielectrics; composites; lamination | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4861885-A | Allylbicyclo[2.2.1]hept-5-ene-2-carboxylic acid amides | CIBA-GEIGY CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |