Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 12/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358804 | 0.85 | LMNA (0.41) | BCHEMAPK1P2RX7 | |
| SCHEMBL10358817 | 0.85 | TSHR (0.46) | HPGDMAPK1EPHX2KMT2A | |
| SCHEMBL9803151 | 0.81 | TSHR (0.42) | HPGDMAPK1EPHX2P2RX7MEN1 | |
| SCHEMBL10359171 | 0.76 | — | — | |
| SCHEMBL10359173 | 0.75 | EPHX1 (0.40) | EPHX2MEN1KMT2A | |
| SCHEMBL10701273 | 0.71 | ALDH1A1 (0.43) | HPGDMAPK1EPHX2P2RX7MEN1 | |
| SCHEMBL28019638 | 0.65 | BCHE (0.55) | BCHEHPGDMAPK1EPHX2P2RX7 | |
| SCHEMBL27810920 | 0.65 | BCHE (0.61) | BCHEHPGDKCNA3 | |
| SCHEMBL9803398 | 0.65 | LMNA (0.45) | MEN1KMT2A | |
| SCHEMBL19641338 | 0.65 | BCHE (0.48) | BCHEHPGDKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226544-B1 | Derivatives of alkyl-bicyclo[2.2.1]hept-5-ene-2-carboxylic acids | CIBA-GEIGY AG (CH) | 1990-03-07 | — | — | EP | disclosed |
| EP-0226544-A2 | Derivatives of alkyl-bicyclo[2.2.1]hept-5-ene-2-carboxylic acids | CIBA-GEIGY AG (CH) | 1987-06-24 | — | — | EP | disclosed |